The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphotransferase system, lactose/cellobiose-type IIA subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: PTS system, lactose-specific IIa component

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
126 A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) P69791 (/IPI) P69791 (/IPI) P69791 (/IPI)
(116 more)
Protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity GO:0090566
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).
119 P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA)
(109 more)
Protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity GO:0090566
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).
119 P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA)
(109 more)
Cellobiose transmembrane transporter activity GO:0019191
Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
106 A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS)
(96 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
7 A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI) A0A0H2UNP1 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
119 P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA)
(109 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
119 P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA) P69791 (/RCA)
(109 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
119 P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA)
(109 more)
N,N'-diacetylchitobiose import GO:1902815
The directed movement of N,N'-diacetylchitobiose into a cell or organelle.
119 P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA)
(109 more)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
106 A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS) A0A0J1HTH8 (/ISS)
(96 more)
Cellobiose transport GO:0019533
The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
71 A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS) A0A1Q4M9Z1 (/ISS)
(61 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
119 P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA) P69791 (/IDA)
(109 more)