The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
3072 - - 98.4
2
1202
3D
1hciB01 - 82.6
3
1199
3D
1hciB04 - 95.0
4
1153
3D
1quuA01 - 89.7
5
1141
3D
1quuA02 - 96.7
6
1131 - - 89.3
7
1015
3D
2spcB00 - 99.7
8
843 - - 100.0
9
841
3D
2iakA01 - 93.2
10
786 - - 99.6
11
772
3D
3lbxB02 - 98.7
12
731 - - 71.3
13
665
3D
3fb2B01 - 99.2
14
661 - - 79.3
15
639 - - 50.3
16
629 - - 82.4
17
609
3D
1u5pA01 - 98.7
18
601
3D
3lbxB01 - 94.5
19
585
3D
3kbuB00 - 94.4
20
580
3D
1u4qB03 - 95.8
21
572 - - 73.3
22
557 - - 74.5
23
551 - - 81.5
24
548 - - 60.3
25
544 - - 71.2
26
521 - - 68.2
28
505
3D
1s35A01 - 91.4
27
504 - - 79.1
29
500 - - 93.1
31
479 - - 85.5
30
479 - - 97.2
32
469 - - 70.7
33
468 - - 97.1
34
460 - - 78.7
35
430 - - 77.1
36
418
3D
2odvA01 - 71.6
37
404
3D
1u5pA02 - 70.0
38
384 - - 65.1
39
378 - - 94.6
40
378 - - 66.8
41
378 - - 72.2
42
376 - - 78.1
43
372 - - 82.7
44
366 - - 78.7
45
365 - - 76.2
46
365 - - 49.2
47
362 - - 81.1
48
361 - - 58.5
49
356
3D
1s35A02 - 95.7
50
341 - - 87.6
51
337 - - 66.3
52
337 - - 71.2
53
336 - - 89.7
54
336 - - 54.7
55
335 - - 74.2
56
335 - - 93.0
57
333 - - 55.0
58
332 - - 64.9
59
329 - - 87.8
60
328 - - 77.4
61
327 - - 69.5
62
323 - - 62.8
65
321
3D
5j1gB00 - 84.1
63
320 - - 65.0
64
319 - - 60.8
66
317 - - 38.5
67
315 - - 76.1
68
312 - - 90.8
69
310 - - 58.2
70
303 - - 89.7
71
300 - - 56.0
75
293
3D
3uunB00 - 91.0
72
292 - - 68.7
73
290 - - 79.5
76
288
3D
2odvA02 - 65.6
74
287 - - 66.8
77
284 - - 75.6
78
284 - - 77.5
79
276 - - 54.3
81
273 - - 94.0
80
273 - - 25.7
82
269 - - 91.8
83
266 - - 73.4
84
258 - - 64.6
85
254 - - 79.5
86
254 - - 12.8
87
252 - - 79.1
88
251 - - 71.8
89
250 - - 65.4
90
248 - - 75.8
91
247 - - 78.9
92
247 - - 94.9
93
246 - - 83.8
94
239 - - 72.6
95
235 - - 97.0
96
231 - - 50.4
97
229 - - 64.6
98
220 - - 76.8
99
199 - - 89.6
100
198 - - 55.8
101
186 - - 65.2
102
179 - - 74.1
103
177 - - 67.2
104
176 - - 49.7
105
173 - - 72.9
106
172 - - 86.0
107
166 - - 17.9
108
161 - - 76.9
109
160 - - 96.7
110
160 - - 37.3
112
159 - - 89.1
111
159 - - 60.1
113
157 - - 56.8
114
156 - - 89.5
115
151 - - 55.5
116
148 - - 76.5
118
147 - - 74.7
119
147 - - 66.7
117
147 - - 61.1
120
140 - - 44.6
121
138 - - 86.0
123
136
3D
3r6nB01 - 74.1
122
135 - - 71.5
124
133 - - 39.6
125
132 - - 79.2
127
126 - - 93.3
126
126 - - 64.4
128
123 - - 41.4
129
119 - - 36.5
130
118 - - 83.1
131
117 - - 72.5
135
116 - - 95.9
132
116 - - 64.8
133
116 - - 61.7
134
116 - - 64.4
139
114 - - 65.4
136
114 - - 35.5
138
114 - - 91.9
137
114 - - 81.6
140
110 - - 76.1
141
104 - - 75.8
142
102 - - 82.7
143
101 - - 75.8
144
100 - - 55.7
145
98 - - 90.2
146
92 - - 66.4
147
90 - - 44.7
148
88 - - 41.0
151
86 - - 24.1
150
86 - - 34.3
149
86 - - 70.8
152
84 - - 95.3
153
81 - - 87.6
155
80 - - 72.1
154
80 - - 47.8
156
78 - - 72.8
157
77 - - 55.8
158
75 - - 71.5
160
74 - - 83.2
159
74 - - 59.6
161
73 - - 8.6
163
72 - - 72.0
162
72 - - 57.4
164
71 - - 60.3
165
70 - - 32.5
166
70 - - 59.2
168
69 - - 35.6
167
69 - - 49.5
171
68 - - 97.8
170
68 - - 70.9
169
68 - - 67.1
172
67 - - 78.7
173
67 - - 85.7
174
66 - - 92.3
175
65 - - 25.7
177
64 - - 58.2
176
64 - - 56.9
178
63 - - 84.7
179
62 - - 32.6
180
59 - - 86.6
181
59 - - 69.1
182
58 - - 58.6
184
58 - - 55.7
183
58 - - 57.4
185
57 - - 63.1
186
56 - - 64.2
189
55 - - 60.1
187
55 - - 32.8
188
55 - - 69.9
190
54 - - 70.7
193
52 - - 41.8
191
52 - - 82.7
192
52 - - 66.4
194
51 - - 32.8
195
51 - - 85.8
196
49 - - 17.3
197
48 - - 23.3
198
48 - - 22.6
199
47 - - 14.4
200
46 - - 42.7
202
46 - - 19.0
201
46 - - 18.4
205
45 - - 15.2
203
45 - - 20.4
204
45 - - 27.9
206
43 - - 49.2
207
43 - - 26.3
208
42 - - 14.2
209
42 - - 16.5
210
42 - - 74.9
211
41 - - 51.4
213
41 - - 48.9
212
41 - - 47.4
214
41 - - 88.1
218
40 - - 36.3
215
40 - - 32.1
217
40 - - 44.6
216
40 - - 51.1
219
40 - - 19.2
220
39 - - 16.1
221
39 - - 33.6
222
39 - - 55.0
224
38 - - 66.1
225
38 - - 92.5
223
38 - - 8.8
226
37 - - 42.4
227
37 - - 10.5
229
37 - - 97.3
228
37 - - 6.9
230
36 - - 80.5
231
36 - - 63.9
232
35 - - 74.1
233
35 - - 31.4
234
34 - - 78.4
235
34 - - 24.6
236
33 - - 52.0
237
33 - - 46.4
238
33 - - 29.1
240
32 - - 44.8
239
32 - - 33.4
244
31 - - 17.0
245
31 - - 15.1
241
31 - - 36.5
243
31 - - 73.4
242
31 - - 43.4
246
30 - - 38.8
247
30 - - 87.3
248
30 - - 43.4
251
29 - - 29.4
250
29 - - 47.8
249
29 - - 37.2
252
29 - - 34.7
254
28 - - 41.1
256
28 - - 22.1
255
28 - - 31.2
257
28 - - 5.2
253
28 - - 92.3
260
27 - - 91.9
262
27 - - 19.4
259
27 - - 94.6
261
27 - - 10.2
258
27 - - 53.0
265
26 - - 9.9
264
26 - - 25.6
263
26 - - 15.7
267
26 - - 67.7
266
26 - - 21.5
270
25 - - 8.4
269
25 - - 6.3
268
25 - - 8.3
271
25 - - 48.6
272
24 - - 64.4
275
24 - - 35.4
274
24 - - 30.1
273
24 - - 31.0
278
23 - - 11.5
276
23 - - 36.2
277
23 - - 95.3
279
22 - - 76.4
280
22 - - 50.6
281
22 - - 43.9
282
22 - - 83.6
285
21 - - 35.6
286
21 - - 64.5
284
21 - - 33.2
283
21 - - 43.7
288
20 - - 10.8
287
20 - - 43.8
289
20 - - 63.0
290
20 - - 13.7
295
19 - - 39.2
300
19 - - 82.2
296
19 - - 73.8
294
19 - - 52.2
293
19 - - 85.8
292
19 - - 45.6
291
19 - - 48.1
299
19 - - 76.0
298
19 - - 24.1
297
19 - - 21.5
308
18 - - 53.1
301
18 - - 41.1
303
18 - - 16.3
307
18 - - 87.8
302
18 - - 53.0
305
18 - - 29.0
304
18 - - 25.7
306
18 - - 58.2
311
17 - - 30.2
312
17 - - 33.6
309
17 - - 80.0
310
17 - - 43.1
316
17 - - 12.2
314
17 - - 21.0
315
17 - - 8.1
317
17 - - 2.4
313
17 - - 43.0
325
16 - - 17.6
324
16 - - 10.2
323
16 - - 12.3
322
16 - - 19.9
327
16 - - 7.6
320
16 - - 17.4
326
16 - - 12.7
321
16 - - 15.8
319
16 - - 59.7
318
16 - - 70.7
331
15 - - 29.7
337
15 - - 20.0
340
15 - - 34.1
329
15 - - 68.8
333
15 - - 21.3
330
15 - - 22.0
332
15 - - 22.0
335
15 - - 12.3
334
15 - - 12.5
338
15 - - 84.5
328
15 - - 63.0
339
15 - - 40.7
336
15 - - 19.7
350
14 - - 51.7
348
14 - - 25.3
342
14 - - 38.4
341
14 - - 26.1
349
14 - - 12.5
346
14 - - 6.2
347
14 - - 20.3
343
14 - - 15.6
345
14 - - 3.8
344
14 - - 7.8
358
13 - - 10.1
351
13 - - 37.6
352
13 - - 19.4
359
13 - - 48.9
353
13 - - 21.8
354
13 - - 30.7
355
13 - - 71.4
357
13 - - 8.9
356
13 - - 16.8
360
12 - - 46.2
361
12 - - 60.9
363
12 - - 20.9
362
12 - - 16.8
364
11 - - 25.4
367
11 - - 9.3
370
11 - - 6.3
373
11 - - 47.1
366
11 - - 22.5
369
11 - - 15.5
372
11 - - 82.5
368
11 - - 16.9
374
11 - - 64.5
371
11 - - 11.7
365
11 - - 18.2
378
10 - - 18.8
382
10 - - 3.4
379
10 - - 11.8
380
10 - - 12.2
381
10 - - 4.8
386
10 - - 47.8
375
10 - - 87.9
385
10 - - 15.8
377
10 - - 33.8
384
10 - - 5.9
376
10 - - 26.6
383
10 - - 9.9
389
9 - - 58.2
388
9 - - 16.2
391
9 - - 12.7
405
9 - - 17.1
392
9 - - 40.6
399
9 - - 1.9
400
9 - - 11.0
394
9 - - 70.8
393
9 - - 18.2
387
9 - - 8.7
395
9 - - 43.9
402
9 - - 18.3
398
9 - - 2.5
397
9 - - 18.7
401
9 - - 22.8
404
9 - - 16.5
396
9 - - 1.4
403
9 - - 83.2
390
9 - - 28.5
410
8 - - 7.8
415
8 - - 3.0
417
8 - - 44.8
416
8 - - 70.1
413
8 - - 23.0
414
8 - - 20.1
409
8 - - 15.6
412
8 - - 0.5
411
8 - - 11.2
407
8 - - 47.5
406
8 - - 24.7
408
8 - - 65.2
418
7 - - 17.5
427
7 - - 59.5
426
7 - - 12.3
428
7 - - 18.4
425
7 - - 8.5
424
7 - - 2.6
429
7 - - 57.8
423
7 - - 22.7
422
7 - - 18.5
420
7 - - 11.8
419
7 - - 66.4
421
7 - - 13.3
437
6 - - 4.6
431
6 - - 80.2
430
6 - - 51.7
438
6 - - 9.7
436
6 - - 15.9
441
6 - - 2.4
432
6 - - 11.4
434
6 - - 12.2
442
6 - - 41.6
433
6 - - 9.2
440
6 - - 1.2
472
6
3D
3edvB01 - 16.9
439
6 - - 13.8
435
6 - - 14.8
443
5 - - 3.4
447
5 - - 36.3
444
5 - - 6.1
445
5 - - 15.1
446
5 - - 3.0
449
5 - - 42.0
448
5 - - 42.7
450
5 - - 56.2
463
4 - - 0.0
458
4 - - 1.9
451
4 - - 59.1
454
4 - - 68.5
460
4 - - 8.1
453
4 - - 70.3
452
4 - - 47.2
456
4 - - 3.8
468
4 - - 14.2
475
4 - - 12.7
462
4 - - 7.0
477
4 - - 26.4
476
4 - - 14.5
469
4 - - 9.9
461
4 - - 0.0
471
4 - - 11.1
465
4 - - 6.6
479
4 - - 56.3
467
4 - - 0.9
474
4 - - 0.6
464
4 - - 7.2
478
4 - - 64.9
459
4 - - 13.4
455
4 - - 0.0
457
4 - - 8.7
470
4 - - 13.5
466
4 - - 0.0
473
4 - - 0.0
512
3 - - 33.1
495
3 - - 7.8
486
3 - - 57.5
509
3 - - 29.1
485
3 - - 25.0
488
3 - - 33.9
480
3 - - 17.8
508
3 - - 7.5
507
3 - - 10.0
506
3 - - 0.0
496
3 - - 0.0
493
3 - - 4.8
498
3 - - 1.0
483
3 - - 12.5
500
3 - - 11.5
510
3 - - 45.0
501
3 - - 0.7
490
3 - - 45.0
492
3 - - 29.8
511
3 - - 33.7
489
3 - - 23.4
502
3 - - 14.0
481
3 - - 22.9
503
3 - - 1.2
484
3 - - 6.3
497
3 - - 0.5
504
3 - - 13.6
487
3 - - 36.0
494
3 - - 1.1
505
3 - - 0.0
482
3 - - 24.6
499
3 - - 7.5
491
3 - - 10.6
559
2 - - 0.0
560
2 - - 2.1
580
2 - - 1.9
517
2 - - 0.0
578
2 - - 1.6
572
2 - - 0.0
540
2 - - 0.0
527
2 - - 0.0
571
2 - - 1.2
548
2 - - 41.9
594
2 - - 0.0
569
2 - - 10.4
523
2 - - 0.0
586
2 - - 0.6
595
2 - - 0.0
536
2 - - 17.4
579
2 - - 0.5
535
2 - - 6.9
541
2 - - 7.0
558
2 - - 0.0
573
2 - - 1.3
567
2 - - 8.3
581
2 - - 2.0
605
2 - - 0.8
607
2 - - 1.0
568
2 - - 8.6
525
2 - - 0.0
582
2 - - 0.0
534
2 - - 0.7
557
2 - - 31.0
515
2 - - 0.0
606
2 - - 0.0
519
2 - - 0.4
590
2 - - 9.1
545
2 - - 36.5
588
2 - - 0.0
617
2 - - 11.4
542
2 - - 0.0
574
2 - - 0.0
566
2 - - 0.0
526
2 - - 0.0
533
2 - - 0.0
604
2 - - 3.5
556
2 - - 27.8
514
2 - - 1.5
610
2 - - 0.0
513
2 - - 0.0
615
2 - - 2.2
549
2 - - 39.7
575
2 - - 0.0
589
2 - - 1.4
614
2 - - 40.2
543
2 - - 0.0
583
2 - - 1.0
591
2 - - 0.0
539
2 - - 8.2
603
2 - - 1.6
565
2 - - 2.2
620
2 - - 0.0
520
2 - - 1.0
532
2 - - 0.0
611
2 - - 6.0
584
2 - - 0.5
585
2 - - 0.6
622
2 - - 27.5
553
2 - - 29.8
555
2 - - 27.4
619
2 - - 1.1
538
2 - - 0.0
621
2 - - 35.8
524
2 - - 0.0
554
2 - - 26.6
552
2 - - 53.7
521
2 - - 0.0
598
2 - - 1.3
602
2 - - 5.1
612
2 - - 0.0
564
2 - - 2.6
563
2 - - 4.9
593
2 - - 5.0
576
2 - - 4.3
616
2 - - 43.9
544
2 - - 8.4
623
2 - - 39.8
562
2 - - 0.0
518
2 - - 0.0
608
2 - - 28.7
546
2 - - 0.0
537
2 - - 0.0
522
2 - - 1.3
599
2 - - 7.1
609
2 - - 1.8
587
2 - - 1.1
601
2 - - 0.0
551
2 - - 0.0
529
2 - - 0.0
624
2 - - 36.0
531
2 - - 0.0
596
2 - - 1.8
516
2 - - 0.0
613
2 - - 0.0
577
2 - - 0.0
561
2 - - 0.0
600
2 - - 0.0
550
2 - - 0.0
592
2 - - 6.1
547
2 - - 0.0
530
2 - - 0.6
570
2 - - 0.0
618
2 - - 9.7
597
2 - - 0.0
528
2 - - 0.0
882
1 - - 0.0
737
1 - - 0.0
767
1 - - 0.0
798
1 - - 0.0
805
1 - - 0.0
722
1 - - 0.0
846
1 - - 0.0
634
1 - - 0.0
695
1 - - 0.0
728
1 - - 0.0
742
1 - - 0.0
889
1 - - 0.0
675
1 - - 0.0
684
1 - - 0.0
861
1 - - 0.0
833
1 - - 0.0
825
1 - - 0.0
859
1 - - 0.0
739
1 - - 0.0
876
1 - - 0.0
662
1 - - 0.0
783
1 - - 0.0
758
1 - - 0.0
706
1 - - 0.0
789
1 - - 0.0
834
1 - - 0.0
772
1 - - 0.0
627
1 - - 0.0
715
1 - - 0.0
653
1 - - 0.0
716
1 - - 0.0
686
1 - - 0.0
685
1 - - 0.0
743
1 - - 0.0
778
1 - - 0.0
720
1 - - 0.0
723
1 - - 0.0
637
1 - - 0.0
690
1 - - 0.0
752
1 - - 0.0
835
1 - - 0.0
862
1 - - 0.0
683
1 - - 0.0
765
1 - - 0.0
881
1 - - 0.0
784
1 - - 0.0
762
1 - - 0.0
638
1 - - 0.0
734
1 - - 0.0
875
1 - - 0.0
824
1 - - 0.0
661
1 - - 0.0
800
1 - - 0.0
678
1 - - 0.0
773
1 - - 0.0
813
1 - - 0.0
644
1 - - 0.0
759
1 - - 0.0
851
1 - - 0.0
694
1 - - 0.0
816
1 - - 0.0
652
1 - - 0.0
874
1 - - 0.0
791
1 - - 0.0
796
1 - - 0.0
844
1 - - 0.0
787
1 - - 0.0
775
1 - - 0.0
746
1 - - 0.0
744
1 - - 0.0
888
1 - - 0.0
633
1 - - 0.0
718
1 - - 0.0
700
1 - - 0.0
868
1 - - 0.0
672
1 - - 0.0
764
1 - - 0.0
769
1 - - 0.0
803
1 - - 0.0
853
1 - - 0.0
751
1 - - 0.0
724
1 - - 0.0
666
1 - - 0.0
691
1 - - 0.0
860
1 - - 0.0
677
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