The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Single helix bin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Quinol--cytochrome-c reductase. [EC: 7.1.1.8]
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2).
  • The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain.
  • It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria.
  • The mammalian enzyme contains cytochromes b-562, b-566 and c(1), and a 2-iron ferredoxin.
  • Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non- cytoplasmic compartment (cf. EC 1.6.99.3).
  • Formerly EC 1.10.2.2.
23 A0A0E2PAP9 A0A0F3MTL1 A0A0Q0URW2 A0A182D4D6 A0A1V5EJ19 A0A2A6MMU3 A0A3G6WS56 A3PFR7 D5ANZ2 D5AWJ4
(13 more...)
Receptor protein-tyrosine kinase. [EC: 2.7.10.1]
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
  • The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans.
  • In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies.
  • Formerly EC 2.7.1.112.
4 A0A024QZA8 P29317 Q03145 Q1KL86