The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
6-Phosphogluconate Dehydrogenase, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: 6-phosphogluconate dehydrogenase, decarboxylating

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). [EC: 1.1.1.44]
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.
  • Highly specific for NADP(+).
  • Cf. EC 1.1.1.343.
118 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A0L8VQ98 A0A120SFK0 A0A120SFK0
(108 more...)