The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44: cAMP-responsive element-binding protein-like 2 iso...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
14 O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA) O60519 (/ISA)
(4 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
14 O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS) O60519 (/NAS)
(4 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
14 O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q0VD32 (/IPI) Q0VD32 (/IPI) Q32M00 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q9VL14 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9VL14 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q9VL14 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
20 A4IGK3 (/ISS) A4IGK3 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(10 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
20 A4IGK3 (/ISS) A4IGK3 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(10 more)
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
20 A4IGK3 (/ISS) A4IGK3 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(10 more)
Positive regulation of lipid biosynthetic process GO:0046889
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
20 A4IGK3 (/ISS) A4IGK3 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(10 more)
Positive regulation of peptidyl-serine phosphorylation GO:0033138
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
17 O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(7 more)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
17 O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(7 more)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
14 O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS)
(4 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
14 O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS)
(4 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q32M00 (/IMP) Q9VL14 (/IMP)
Positive regulation of peptidyl-serine phosphorylation GO:0033138
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
1 Q32M00 (/IMP)
TORC1 signaling GO:0038202
A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
1 Q9VL14 (/IMP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 Q9VL14 (/IMP)
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
1 Q32M00 (/IMP)
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
1 Q32M00 (/IMP)
Positive regulation of lipid biosynthetic process GO:0046889
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
1 Q32M00 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q32M00 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
20 A4IGK3 (/ISS) A4IGK3 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS) O60519 (/ISS)
(10 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
14 O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS) O60519 (/TAS)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q32M00 (/IDA) Q9VL14 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
2 Q0VD32 (/IDA) Q0VD32 (/IDA)