View in Gene3D

CATH Superfamily 1.20.190.20

14-3-3 domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
14-3-3 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4: 14-3-3 protein gamma

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Insulin-like growth factor receptor binding GO:0005159
Interacting selectively and non-covalently with the insulin-like growth factor receptor.
 1 P68253 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
 1 P68253 (/ISS)
Negative regulation of G protein-coupled receptor signaling pathway GO:0045744
Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.
 1 P68251 (/ISS)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
 1 P68253 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.