The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amino acid/polyamine transporter I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Low affinity cationic amino acid transporter 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
4 P30825 (/TAS) P30825 (/TAS) P52569 (/TAS) Q8WY07 (/TAS)
Arginine transmembrane transporter activity GO:0015181
Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
4 B5D5N9 (/IDA) P30823 (/IDA) Q09143 (/IDA) Q09143 (/IDA)
Arginine transmembrane transporter activity GO:0015181
Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
3 P18581 (/ISO) Q09143 (/ISO) Q09143 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P30825 (/IPI) P30825 (/IPI)
Basic amino acid transmembrane transporter activity GO:0015174
Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7.
2 P30823 (/TAS) P52569 (/TAS)
Arginine transmembrane transporter activity GO:0015181
Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
1 P18581 (/IMP)
Arginine transmembrane transporter activity GO:0015181
Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
1 B5D5N9 (/TAS)
L-arginine transmembrane transporter activity GO:0061459
Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
1 P18581 (/IMP)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P30825 (/TAS) P30825 (/TAS) P52569 (/TAS) Q8WY07 (/TAS)
Arginine transport GO:0015809
The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 B5D5N9 (/IDA) Q09143 (/IDA) Q09143 (/IDA)
Arginine transport GO:0015809
The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 P18581 (/ISO) Q09143 (/ISO) Q09143 (/ISO)
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 F1R9X0 (/IMP) Q5U375 (/IMP)
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
2 F1R9X0 (/IMP) Q5U375 (/IMP)
Regulation of TOR signaling GO:0032006
Any process that modulates the frequency, rate or extent of TOR signaling.
2 Q09143 (/ISO) Q09143 (/ISO)
Nitric oxide production involved in inflammatory response GO:0002537
The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
1 P18581 (/IMP)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 P52569 (/TAS)
Nitric oxide biosynthetic process GO:0006809
The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
1 P18581 (/IMP)
Basic amino acid transport GO:0015802
The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P30823 (/TAS)
Arginine transport GO:0015809
The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P30823 (/IMP)
Regulation of TOR signaling GO:0032006
Any process that modulates the frequency, rate or extent of TOR signaling.
1 P30823 (/IMP)
Macrophage activation GO:0042116
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1 P18581 (/IMP)
Regulation of macrophage activation GO:0043030
Any process that modulates the frequency or rate of macrophage activation.
1 P18581 (/IMP)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
1 P18581 (/IMP)
L-arginine transport GO:1902023
The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P18581 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P30825 (/TAS) P30825 (/TAS) P52569 (/TAS) Q8WY07 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 P18581 (/ISO) Q09143 (/ISO) Q09143 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P30825 (/TAS) P30825 (/TAS) P52569 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P30823 (/IDA) P52569 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P30825 (/HDA) P30825 (/HDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q09143 (/IC) Q09143 (/IC)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 P30825 (/IDA) P30825 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q09143 (/ISO) Q09143 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 B5D5N9 (/IC)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P52569 (/TAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P18581 (/IDA)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
1 P52569 (/IDA)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
1 P18581 (/ISO)