The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amino acid/polyamine transporter I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: large neutral amino acids transporter small subuni...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 18 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P63115 (/IPI) P63115 (/IPI) Q9UHI5 (/IPI) Q9UHI5 (/IPI) Q9UHI5 (/IPI) Q9UHI5 (/IPI) Q9UHI5 (/IPI)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
6 Q9N1Q4 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
6 Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9WVR6 (/ISS)
Peptide antigen binding GO:0042605
Interacting selectively and non-covalently with an antigen peptide.
6 Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9WVR6 (/ISS)
Organic cation transmembrane transporter activity GO:0015101
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
5 Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
5 Q9UHI5 (/EXP) Q9UHI5 (/EXP) Q9UHI5 (/EXP) Q9UHI5 (/EXP) Q9UHI5 (/EXP)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
5 Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
5 Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
3 P63115 (/IDA) P63115 (/IDA) Q9NS82 (/IDA)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
2 P63115 (/ISO) P63115 (/ISO)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
2 P63116 (/ISS) P63116 (/ISS)
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
1 Q9QXW9 (/ISA)
Organic cation transmembrane transporter activity GO:0015101
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
1 Q9QXW9 (/ISO)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
1 Q9QXW9 (/ISO)
L-amino acid transmembrane transporter activity GO:0015179
Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
1 Q9QXW9 (/IDA)
L-serine transmembrane transporter activity GO:0015194
Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.
1 Q9NS82 (/TAS)
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
1 Q9QXW9 (/ISO)
Peptide antigen binding GO:0042605
Interacting selectively and non-covalently with an antigen peptide.
1 Q9N1Q4 (/IPI)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 P63116 (/ISS) P63116 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9UHI5 (/ISS) Q9WVR6 (/ISS)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 Q9NS82 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
6 Q9NS82 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
5 Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
5 Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
5 Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS)
Metal ion homeostasis GO:0055065
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
5 Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS) Q9UHI5 (/NAS)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P63115 (/IDA) P63115 (/IDA) Q9N1Q4 (/IDA) Q9NS82 (/IDA)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P63115 (/ISO) P63115 (/ISO)
D-alanine transport GO:0042941
The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P63115 (/IMP) P63115 (/IMP)
D-serine transport GO:0042942
The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P63115 (/IMP) P63115 (/IMP)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9QXW9 (/ISA)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9QXW9 (/ISO)
L-amino acid transport GO:0015807
The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9QXW9 (/IDA)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 Q9NS82 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 Q9NS82 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS) Q9UHI5 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA) Q9UHI5 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P63115 (/NAS) P63115 (/NAS) Q9NS82 (/NAS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P63116 (/IDA) P63116 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P63115 (/ISO) P63115 (/ISO)
Apical dendrite GO:0097440
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
2 P63116 (/IDA) P63116 (/IDA)
Apical dendrite GO:0097440
A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
2 P63115 (/ISO) P63115 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9QXW9 (/ISA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9QXW9 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9NS82 (/TAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9N1Q4 (/TAS)