The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amino acid/polyamine transporter I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: B(0,+)-type amino acid transporter 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
5 Q5BIK9 (/ISS) Q8IR48 (/ISS) Q9VY26 (/ISS) X2JDR1 (/ISS) X2JK78 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P82251 (/IPI) Q50E62 (/IPI) Q9QXA6 (/IPI) Q9QXA6 (/IPI)
L-cystine transmembrane transporter activity GO:0015184
Enables the transfer of L-cystine from one side of a membrane to the other.
4 P82252 (/ISS) Q9N1R6 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Peptide antigen binding GO:0042605
Interacting selectively and non-covalently with an antigen peptide.
4 P82251 (/ISS) P82252 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
3 P82252 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
2 P82252 (/IDA) Q50E62 (/IDA)
Amino acid transmembrane transporter activity GO:0015171
Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
L-cystine transmembrane transporter activity GO:0015184
Enables the transfer of L-cystine from one side of a membrane to the other.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
1 Q9N1R6 (/IDA)
Neutral amino acid transmembrane transporter activity GO:0015175
Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
1 P82251 (/IMP)
L-cystine transmembrane transporter activity GO:0015184
Enables the transfer of L-cystine from one side of a membrane to the other.
1 P82251 (/IMP)
Peptide antigen binding GO:0042605
Interacting selectively and non-covalently with an antigen peptide.
1 Q9N1R6 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q50E62 (/IDA)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transmembrane transport GO:0003333
The process in which an amino acid is transported across a membrane.
5 Q5BIK9 (/ISS) Q8IR48 (/ISS) Q9VY26 (/ISS) X2JDR1 (/ISS) X2JK78 (/ISS)
L-cystine transport GO:0015811
The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P82252 (/ISS) Q9N1R6 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 P82252 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P82252 (/IDA) Q50E62 (/IDA)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
L-cystine transport GO:0015811
The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P82251 (/TAS)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9N1R6 (/IDA)
Neutral amino acid transport GO:0015804
The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P82251 (/IMP)
L-cystine transport GO:0015811
The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P82251 (/IMP)
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
1 P82251 (/TAS)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 P82251 (/TAS)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P82251 (/ISS) Q9N1R6 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
4 P82252 (/ISS) Q9N1R6 (/ISS) Q9QXA6 (/ISS) Q9QXA6 (/ISS)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
3 P82251 (/IDA) Q9QXA6 (/IDA) Q9QXA6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
2 Q9QXA6 (/ISO) Q9QXA6 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
2 P82252 (/ISS) Q9N1R6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8IR48 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P82252 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P82251 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P82251 (/TAS)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 Q8IR48 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9N1R6 (/IC)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 P82251 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q50E62 (/IDA)