The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Sodium/glucose cotransporter
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Urea active transporter

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Urea transmembrane transporter activity GO:0015204
Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
11 P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) Q5BGB2 (/IMP) Q5BGB2 (/IMP) Q5BGB2 (/IMP) Q7XBS0 (/IMP)
(1 more)
Spermidine transmembrane transporter activity GO:0015606
Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
7 A0A1D8PDB5 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP)
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
6 P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA)
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
6 P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP)
Spermidine transmembrane transporter activity GO:0015606
Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
6 P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA)
Urea transmembrane transporter activity GO:0015204
Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
4 A0A1D8PDB5 (/ISO) O94469 (/ISO) Q8TFG0 (/ISO) Q9URY6 (/ISO)
Urea transmembrane transporter activity GO:0015204
Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
2 F4KD71 (/IDA) F4KD71 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Urea transport GO:0015840
The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
10 A0A1D8PDB5 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) Q5BGB2 (/IMP) Q5BGB2 (/IMP) Q5BGB2 (/IMP)
Spermidine transport GO:0015848
The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
7 A0A1D8PDB5 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP)
Putrescine transport GO:0015847
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
6 P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA)
Putrescine transport GO:0015847
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
6 P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP)
Spermidine transport GO:0015848
The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6 P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA)
Urea catabolic process GO:0043419
The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
6 P33413 (/IEP) P33413 (/IEP) P33413 (/IEP) P33413 (/IEP) P33413 (/IEP) P33413 (/IEP)
Urea transmembrane transport GO:0071918
The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
3 O94469 (/ISO) Q8TFG0 (/ISO) Q9URY6 (/ISO)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
2 F4KD71 (/IEP) F4KD71 (/IEP)
Urea transmembrane transport GO:0071918
The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2 F4KD71 (/IDA) F4KD71 (/IDA)
Urea transmembrane transport GO:0071918
The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
2 Q7XBS0 (/IMP) Q7XBS0 (/IMP)
Urea transport GO:0015840
The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
1 A0A1D8PDB5 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 F4KD71 (/IDA) F4KD71 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) P33413 (/IDA) Q7XBS0 (/IDA) Q7XBS0 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
7 P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) Q8TFG0 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP) P33413 (/IMP)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
6 P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA) P33413 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A1D8PDB5 (/ISO) O94469 (/ISO) Q8TFG0 (/ISO) Q9URY6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9URY6 (/HDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 Q9URY6 (/HDA)