The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhomboid-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Putative inactive rhomboid protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q6PJF5 (/IPI) Q80WQ6 (/IPI) Q96CC6 (/IPI) Q96CC6 (/IPI)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of protein secretion GO:0050709
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
13 A0JPA1 (/ISS) A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q00M95 (/ISS) Q499S9 (/ISS)
(3 more)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
10 A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q499S9 (/ISS) Q6GMF8 (/ISS) Q6PIX5 (/ISS)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
10 A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q499S9 (/ISS) Q6GMF8 (/ISS) Q6PIX5 (/ISS)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
10 A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q499S9 (/ISS) Q6GMF8 (/ISS) Q6PIX5 (/ISS)
Regulation of proteasomal protein catabolic process GO:0061136
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
10 A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q499S9 (/ISS) Q6GMF8 (/ISS) Q6PIX5 (/ISS)
Negative regulation of protein secretion GO:0050709
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
3 Q80WQ6 (/IDA) Q96CC6 (/IDA) Q96CC6 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
2 Q96CC6 (/IMP) Q96CC6 (/IMP)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
2 Q96CC6 (/IMP) Q96CC6 (/IMP)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
2 Q96CC6 (/IMP) Q96CC6 (/IMP)
Regulation of protein secretion GO:0050708
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
2 Q96CC6 (/IMP) Q96CC6 (/IMP)
Regulation of proteasomal protein catabolic process GO:0061136
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
2 Q96CC6 (/IDA) Q96CC6 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q6PIX5 (/ISO)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 Q6PIX5 (/ISO)
Regulation of epidermal growth factor receptor signaling pathway GO:0042058
Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 Q6PIX5 (/ISO)
Regulation of protein secretion GO:0050708
Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
1 Q6PIX5 (/ISO)
Negative regulation of protein secretion GO:0050709
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
1 Q6PIX5 (/ISO)
Regulation of proteasomal protein catabolic process GO:0061136
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
1 Q6PIX5 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
13 A0JPA1 (/ISS) A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q00M95 (/ISS) Q499S9 (/ISS)
(3 more)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
10 A7YWH9 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) A9L8T6 (/ISS) B0VX73 (/ISS) B0VX73 (/ISS) B1MT31 (/ISS) Q499S9 (/ISS) Q6GMF8 (/ISS) Q6PIX5 (/ISS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
3 Q80WQ6 (/IDA) Q96CC6 (/IDA) Q96CC6 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2 Q96CC6 (/IDA) Q96CC6 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q6PIX5 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q6PIX5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q6PJF5 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q80WQ6 (/ISO)