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CATH Superfamily 1.20.1510.10

Cation efflux protein transmembrane domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cation efflux protein transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25: Zinc transporter 35C, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion transmembrane transporter activity GO:0005385
Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
 2 Q8IP48 (/IC) Q9V471 (/IC)
Zinc efflux transmembrane transporter activity GO:0022883
Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.
 1 Q9V471 (/IGI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
 2 Q8IP48 (/IMP) Q9V471 (/IMP)
Detoxification of zinc ion GO:0010312
Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.
 2 Q8IP48 (/IMP) Q9V471 (/IMP)
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
 1 Q9V471 (/IMP)
Zinc ion transmembrane transport GO:0071577
A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
 1 Q9V471 (/IGI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
 2 Q8IP48 (/IDA) Q9V471 (/IDA)