The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

ATP synthase alpha/beta chain, C-terminal domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: ATP synthase alpha/beta chain, C-terminal domain

Structural domains comprising this superfamily share the structure of the C-terminal domain of both alpha and beta chains of ATP synthase. Generally ATPases use the energy from a proton gradient, using the flux of ions across the membrane via the ATPase proton channel, to drive ATP; however, some work in reverse using the energy from the hydrolysis of ATP to create a proton gradient. There are 5 different types of ATPases, which can differ in function, structure and type of ions they transport. The alpha and beta (or A and B) subunits are found in 3 of the different ATPases (F, -V-, and A-). The alpha/A and beta/B subunits are comprised of 3 domains, each centred on the ATP-binding pocket (PFAM:PF00306).

GO Diversity

Unique GO annotations
73 Unique GO terms

EC Diversity

Unique EC annotations
2 Unique EC terms

Species Diversity

Unique species annotations
13974 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 195
Domain clusters (>95% seq id): 10
Domain clusters (>35% seq id): 1
Unique PDBs: 49
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 6
Unique EC: 2
Unique GO: 73
Unique Species: 13974