The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NCX, central ion-binding region
".
FunFam 30: Cation/calcium exchanger 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Manganese ion transmembrane transporter activity GO:0005384
Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.
|
1 | Q9LJI2 (/IMP) |
|
Cation transmembrane transporter activity GO:0008324
Enables the transfer of cation from one side of a membrane to the other.
|
1 | Q9LJI2 (/IDA) |
|
Potassium ion transmembrane transporter activity GO:0015079
Enables the transfer of potassium ions (K+) from one side of a membrane to the other.
|
1 | Q9LJI2 (/IMP) |
|
Sodium ion transmembrane transporter activity GO:0015081
Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.
|
1 | Q9LJI2 (/IMP) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9SYG9 (/IDA) Q9SYG9 (/IDA) |
|
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
1 | Q9FKP2 (/IMP) |
|
Cellular cation homeostasis GO:0030003
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
|
1 | Q9LJI2 (/IDA) |
|
Response to cation stress GO:0043157
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
|
1 | Q9LJI2 (/IEP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
|
1 | Q9LJI2 (/IDA) |
|
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
|
1 | Q9LJI2 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9FKP2 (/IDA) |
|
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
|
1 | Q9LJI2 (/IDA) |
|
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
|
1 | Q9LJI2 (/IDA) |