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CATH Superfamily 1.20.140.10

Butyryl-CoA Dehydrogenase, subunit A, domain 3

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Butyryl-CoA Dehydrogenase, subunit A, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: Long-chain specific acyl-CoA dehydrogenase, mitoch...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Long-chain-acyl-CoA dehydrogenase. [EC: 1.3.8.8]
Long-chain-acyl-CoA + electron-transfer flavoprotein = long-chain-2,3- dehydroacyl-CoA + reduced electron-transfer flavoprotein.
  • One of several enzymes that catalyze the first step in fatty acids beta-oxidation.
  • The enzyme from pig liver can accept substrates with acyl chain lengths of 6 to at least 16 carbon atoms.
  • The highest activity was found with C(12), and the rates with C(8) and C(16) were 80% and 70%, respectively.
  • The enzyme from rat can accept substrates with C(8)-C(22).
  • It is most active with C(14) and C(16), and has no activity with C(4), C(6) or C(24).
  • cf. EC 1.3.8.1, EC 1.3.8.8 and EC 1.3.8.9.
  • Formerly EC 1.3.99.3 and EC 1.3.99.13.
 16 A0A480PCQ6 A0A480PCQ6 G7N8T6 G7N8T6 G7N8T6 G7PLB9 G7PLB9 G7PLB9 P15650 P28330
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