The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Bidirectional sugar transporter SWEET

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sugar transmembrane transporter activity GO:0051119
Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
56 A2WR31 (/ISS) A2WR31 (/ISS) A2WR31 (/ISS) A2WR31 (/ISS) A2WSD3 (/ISS) A2WSD8 (/ISS) A2WSD8 (/ISS) A2X3S3 (/ISS) A2X3S3 (/ISS) A2X3S3 (/ISS)
(46 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 Q6NQN5 (/IPI) Q6NQN5 (/IPI) Q84WN3 (/IPI) Q8L9J7 (/IPI) Q8L9J7 (/IPI) Q8LBF7 (/IPI) Q944M5 (/IPI) Q9C9M9 (/IPI) Q9FM10 (/IPI) Q9LH79 (/IPI)
(2 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q5N8J1 (/IPI) Q5N8J1 (/IPI)
Sugar transmembrane transporter activity GO:0051119
Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
2 Q8L9J7 (/IDA) Q8L9J7 (/IDA)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q9LUR4 (/IDA)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q84WN3 (/IMP)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
1 Q9LUR4 (/IDA)
Sucrose transmembrane transporter activity GO:0008515
Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.
1 Q9LUR4 (/IDA)
Sugar transmembrane transporter activity GO:0051119
Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
1 Q9LUR4 (/IMP)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
7 Q84WN3 (/IDA) Q8L9J7 (/IDA) Q8L9J7 (/IDA) Q944M5 (/IDA) Q9C9M9 (/IDA) Q9FM10 (/IDA) Q9LUR4 (/IDA)
Negative regulation of auxin mediated signaling pathway GO:0010930
Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
3 Q6L568 (/IMP) Q6L568 (/IMP) Q6L568 (/IMP)
Galactose transmembrane transport GO:0015757
The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
3 Q6L568 (/IDA) Q6L568 (/IDA) Q6L568 (/IDA)
Auxin transport GO:0060918
The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 Q6L568 (/IMP) Q6L568 (/IMP) Q6L568 (/IMP)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
2 Q84WN3 (/IEP) Q9LUR4 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
2 Q84WN3 (/IEP) Q9LUR4 (/IEP)
Fructose export from vacuole to cytoplasm GO:1902334
The directed movement of fructose from vacuole to cytoplasm.
2 Q84WN3 (/IMP) Q9LUR4 (/IMP)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q9LUR4 (/IEP)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q84WN3 (/IEP)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 Q9LUR4 (/IEP)
Response to absence of light GO:0009646
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
1 Q84WN3 (/IEP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
1 Q9LUR4 (/IEP)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 Q9LUR4 (/IEP)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q84WN3 (/IMP)
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 Q84WN3 (/IEP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
55 A2WR31 (/ISS) A2WR31 (/ISS) A2WR31 (/ISS) A2WR31 (/ISS) A2WSD3 (/ISS) A2WSD8 (/ISS) A2WSD8 (/ISS) A2X3S3 (/ISS) A2X3S3 (/ISS) A2X3S3 (/ISS)
(45 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 Q6L568 (/IDA) Q6L568 (/IDA) Q6L568 (/IDA) Q8L9J7 (/IDA) Q8L9J7 (/IDA) Q944M5 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 Q8L9J7 (/IDA) Q8L9J7 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q8L9J7 (/IDA) Q8L9J7 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8L9J7 (/IDA) Q8L9J7 (/IDA)
Plant-type vacuole membrane GO:0009705
The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
2 Q84WN3 (/IDA) Q9LUR4 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q9C9M9 (/IDA)