The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Arfaptin homology (AH) domain/BAR domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 60: Actin polymerization protein Bzz1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P38822 (/IPI) P38822 (/IPI) Q09746 (/IPI) Q19253 (/IPI) Q75JD4 (/IPI) Q9XUS7 (/IPI)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
2 P38822 (/IMP) P38822 (/IMP)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
1 Q75JD4 (/IDA)
Diacylglycerol binding GO:0019992
Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids.
1 Q09746 (/ISM)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
2 Q54GD0 (/IGI) Q55CK2 (/IGI)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2 P38822 (/IGI) P38822 (/IGI)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
2 P38822 (/IPI) P38822 (/IPI)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P38822 (/IGI) P38822 (/IGI)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 P38822 (/IPI) P38822 (/IPI)
Regulation of actin cytoskeleton organization GO:0032956
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
2 Q19253 (/IGI) Q9XUS7 (/IGI)
Contractile vacuole organization GO:0033298
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.
2 Q54GD0 (/IGI) Q55CK2 (/IGI)
Phototaxis GO:0042331
The directed movement of a motile cell or organism in response to light.
2 Q54GD0 (/IGI) Q55CK2 (/IGI)
Actin nucleation GO:0045010
The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
2 P38822 (/IMP) P38822 (/IMP)
Embryonic ectodermal digestive tract morphogenesis GO:0048613
The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
2 Q19253 (/IGI) Q9XUS7 (/IGI)
Embryonic ectodermal digestive tract morphogenesis GO:0048613
The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
2 Q19253 (/IMP) Q9XUS7 (/IMP)
Regulation of cellular component movement GO:0051270
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
2 Q54GD0 (/IGI) Q55CK2 (/IGI)
Regulation of cellular component movement GO:0051270
Any process that modulates the frequency, rate or extent of the movement of a cellular component.
2 Q54GD0 (/IMP) Q55CK2 (/IMP)
Negative regulation of filopodium assembly GO:0051490
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
2 Q54GD0 (/IMP) Q55CK2 (/IMP)
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
2 Q19253 (/IGI) Q9XUS7 (/IGI)
Negative regulation of protein localization to cell-cell adherens junction GO:1904703
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell adherens junction.
2 Q19253 (/IGI) Q9XUS7 (/IGI)
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2 Q19253 (/IGI) Q9XUS7 (/IGI)
Positive regulation of clathrin-dependent endocytosis GO:2000370
Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2 Q19253 (/IMP) Q9XUS7 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 Q09746 (/ISO)
Vesicle organization GO:0016050
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
1 Q75JD4 (/IGI)
Actin filament polymerization GO:0030041
Assembly of actin filaments by the addition of actin monomers to a filament.
1 Q75JD4 (/IGI)
Sorocarp development GO:0030587
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
1 Q55CK2 (/IMP)
Contractile vacuole organization GO:0033298
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.
1 Q54GD0 (/IMP)
Chemotaxis to cAMP GO:0043327
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
1 Q75JD4 (/IGI)
Negative regulation of filopodium assembly GO:0051490
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 Q54GD0 (/IGI)
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
1 Q09746 (/IMP)
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
1 Q9XUS7 (/IMP)
Response to differentiation-inducing factor 1 GO:1903013
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
1 Q54GD0 (/HDA)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P38822 (/IDA) P38822 (/IDA) Q19253 (/IDA) Q9XUS7 (/IDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
3 P38822 (/IDA) P38822 (/IDA) Q09746 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P38822 (/HDA) P38822 (/HDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 Q19253 (/IDA) Q9XUS7 (/IDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
2 P38822 (/HDA) P38822 (/HDA)
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
2 P38822 (/HDA) P38822 (/HDA)
Intracellular vesicle GO:0097708
Any vesicle that is part of the intracellular region.
2 Q19253 (/IDA) Q9XUS7 (/IDA)
Contractile vacuole GO:0000331
A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory.
1 Q54GD0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9XUS7 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q54GD0 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q75JD4 (/IDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 Q09746 (/HDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q75JD4 (/IDA)
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
1 Q09746 (/HDA)