The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Shigella T3SS effector IpaH domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Type III secretion system effector protein-E3 Ubiq...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI) A0A0H3NF38 (/IPI)
(18 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
16 D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA)
(6 more)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
12 P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP)
(2 more)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
12 P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS)
(2 more)
Ubiquitin protein ligase activity GO:0061630
Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
12 P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP)
(2 more)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
16 D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA)
(6 more)
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
16 D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA)
(6 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
12 D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA)
(2 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
12 P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS)
(2 more)
Protein ubiquitination GO:0016567
The process in which one or more ubiquitin groups are added to a protein.
12 P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS)
(2 more)
Protein secretion by the type III secretion system GO:0030254
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
12 P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS) P0CE12 (/ISS)
(2 more)
Positive regulation of plant-type hypersensitive response GO:0034052
Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.
12 P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP)
(2 more)
Positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway GO:0070430
Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
12 P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP) P0CE12 (/IMP)
(2 more)
Positive regulation of interleukin-8 secretion GO:2000484
Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
12 P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA) P0CE12 (/IDA)
(2 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
4 D0ZVG2 (/TAS) D0ZVG2 (/TAS) D0ZVG2 (/TAS) D0ZVG2 (/TAS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell plasma membrane GO:0020002
The plasma membrane surrounding a host cell.
12 D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA) D0ZPH9 (/IDA)
(2 more)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
4 D0ZVG2 (/IDA) D0ZVG2 (/IDA) D0ZVG2 (/IDA) D0ZVG2 (/IDA)