The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Shigella T3SS effector IpaH domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Invasion plasmid antigen IpaH

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 Q8VSC3 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8VSC3 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8VSC3 (/IPI)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q8VSC3 (/IDA)
Protein K27-linked ubiquitination GO:0044314
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
1 Q8VSC3 (/IDA)
Modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade GO:0085032
Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q8VSC3 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
9 P18009 (/IDA) P18009 (/IDA) P18009 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) P18014 (/IDA) Q8VSC3 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 B2TT54 (/ISS) B2TT54 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) D2AJU0 (/ISS) Q31SH3 (/ISS) Q326Z6 (/ISS) Q3YTH5 (/ISS)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q8VSC3 (/IDA)
Host cell cytosol GO:0044164
The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8VSC3 (/IDA)