The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Interleukin-15/Interleukin-21
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Interleukin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell activation GO:0001775
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
11 O42288 (/IDA) O42288 (/IDA) O42396 (/IDA) O73883 (/IDA) Q06E04 (/IDA) Q06E04 (/IDA) Q5UB38 (/IDA) Q6UG48 (/IDA) Q6UG49 (/IDA) Q7T110 (/IDA)
(1 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
11 O42288 (/IDA) O42288 (/IDA) O42396 (/IDA) O73883 (/IDA) Q06E04 (/IDA) Q06E04 (/IDA) Q5UB38 (/IDA) Q6UG48 (/IDA) Q6UG49 (/IDA) Q7T110 (/IDA)
(1 more)
Positive regulation of lymphocyte proliferation GO:0050671
Any process that activates or increases the rate or extent of lymphocyte proliferation.
11 O42288 (/IDA) O42288 (/IDA) O42396 (/IDA) O73883 (/IDA) Q06E04 (/IDA) Q06E04 (/IDA) Q5UB38 (/IDA) Q6UG48 (/IDA) Q6UG49 (/IDA) Q7T110 (/IDA)
(1 more)
CD8-positive, alpha-beta T cell activation GO:0036037
The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
10 O42288 (/IDA) O42288 (/IDA) O73883 (/IDA) Q06E04 (/IDA) Q06E04 (/IDA) Q5UB38 (/IDA) Q6UG48 (/IDA) Q6UG49 (/IDA) Q7T110 (/IDA) Q8JJ00 (/IDA)
CD4-positive, alpha-beta T cell activation GO:0035710
The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
1 O42396 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.