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CATH Superfamily 1.20.1250.20

MFS general substrate transporter like domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Galactose-proton symporter (Galactose transporter)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Galactose:proton symporter activity GO:0015517
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).
 146 P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA)
(136 more)
L-arabinose transmembrane transporter activity GO:0015147
Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.
 84 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(74 more)
L-arabinose transmembrane transporter activity GO:0015147
Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.
 84 P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP)
(74 more)
Fucose transmembrane transporter activity GO:0015150
Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
 84 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(74 more)
Fucose transmembrane transporter activity GO:0015150
Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
 84 P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP)
(74 more)
Symporter activity GO:0015293
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
 84 P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP)
(74 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Galactose transmembrane transport GO:0015757
The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
 146 P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA) P0AEP1 (/IDA)
(136 more)
Fucose transmembrane transport GO:0015756
The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
 84 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(74 more)
Fucose transmembrane transport GO:0015756
The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
 84 P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP)
(74 more)
L-arabinose transmembrane transport GO:0042882
The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
 84 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(74 more)
L-arabinose transmembrane transport GO:0042882
The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
 84 P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP) P0AE24 (/IMP)
(74 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 230 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(220 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 84 P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA) P0AE24 (/IDA)
(74 more)