The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 65: Putative MFS pantothenate transporter

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pantothenate transmembrane transporter activity GO:0015233
Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
7 O43000 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP)
Biotin transmembrane transporter activity GO:0015225
Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
4 P53241 (/IDA) P53241 (/IDA) P53241 (/IDA) P53241 (/IDA)
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
1 P39709 (/ISS)
Pantothenate transmembrane transporter activity GO:0015233
Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
1 O43000 (/IGI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
6 P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP)
Pantothenate transmembrane transport GO:0015887
The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
6 P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP)
Biotin transport GO:0015878
The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
4 P53241 (/IDA) P53241 (/IDA) P53241 (/IDA) P53241 (/IDA)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
1 P39709 (/IMP)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
1 P39709 (/ISS)
Pantothenate import across plasma membrane GO:0098717
The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.
1 O43000 (/IGI)
Pantothenate import across plasma membrane GO:0098717
The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.
1 O43000 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
11 P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P39709 (/HDA) P53241 (/HDA) P53241 (/HDA) P53241 (/HDA)
(1 more)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
6 P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
6 P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA) P25621 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP) P25621 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 O43000 (/IDA) P53241 (/IDA) P53241 (/IDA) P53241 (/IDA) P53241 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 O43000 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 O43000 (/IC)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P39709 (/ISS)