The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 29: solute carrier family 2, facilitated glucose trans...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
9 P12336 (/ISS) P14246 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q5RET7 (/ISS) Q863Y9 (/ISS) Q8WMN1 (/ISS) Q9WV38 (/ISS)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
8 P11168 (/IDA) P12336 (/IDA) P14142 (/IDA) P19357 (/IDA) P43427 (/IDA) P43427 (/IDA) Q3T9X0 (/IDA) Q9BYW1 (/IDA)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
6 P22732 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS) Q9WV38 (/ISS)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
5 P11168 (/TAS) P14142 (/TAS) P14246 (/TAS) P14672 (/TAS) P22732 (/TAS)
D-glucose transmembrane transporter activity GO:0055056
Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.
5 B0UY92 (/IDA) P12336 (/IDA) P14246 (/IDA) P19357 (/IDA) Q102R8 (/IDA)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
4 P11168 (/IDA) P22732 (/IDA) P43427 (/IDA) P43427 (/IDA)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
4 P14672 (/ISS) Q27994 (/ISS) Q27994 (/ISS) Q9XSC2 (/ISS)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
3 P14142 (/ISO) P14246 (/ISO) Q9WV38 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P14142 (/IPI) P14672 (/IPI) P19357 (/IPI)
Dehydroascorbic acid transmembrane transporter activity GO:0033300
Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.
3 P11168 (/IDA) P12336 (/IDA) P14246 (/IDA)
Urate transmembrane transporter activity GO:0015143
Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
2 Q3T9X0 (/IDA) Q9NRM0 (/IDA)
D-glucose transmembrane transporter activity GO:0055056
Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.
2 P14142 (/ISO) P14246 (/ISO)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
2 P43427 (/IDA) P43427 (/IDA)
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
1 P12336 (/IPI)
Insulin receptor binding GO:0005158
Interacting selectively and non-covalently with the insulin receptor.
1 P14246 (/ISO)
Carbohydrate:proton symporter activity GO:0005351
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).
1 Q9NRM0 (/NAS)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q9WV38 (/IMP)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q9WV38 (/ISO)
Fructose transmembrane transporter activity GO:0005353
Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 P22732 (/TAS)
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
1 P19357 (/IMP)
Insulin-responsive glucose:proton symporter activity GO:0005360
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
1 P14142 (/TAS)
Glucose binding GO:0005536
Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.
1 Q9XSC2 (/ISS)
Urate transmembrane transporter activity GO:0015143
Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
1 Q3T9X0 (/IMP)
Urate transmembrane transporter activity GO:0015143
Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
1 Q3T9X0 (/ISO)
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
1 Q9NRM0 (/TAS)
Dehydroascorbic acid transmembrane transporter activity GO:0033300
Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.
1 P14246 (/ISO)
Fructose binding GO:0070061
Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
1 Q9WV38 (/ISO)

There are 68 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
12 B0UY92 (/IDA) O44827 (/IDA) P11168 (/IDA) P12336 (/IDA) P14142 (/IDA) P14246 (/IDA) P19357 (/IDA) P43427 (/IDA) P43427 (/IDA) Q102R8 (/IDA)
(2 more)
Cellular response to fructose stimulus GO:0071332
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
9 P22732 (/ISS) P43427 (/ISS) P43427 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q5RET7 (/ISS) Q863Y9 (/ISS) Q8WMN1 (/ISS)
Regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044
The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
7 P22732 (/ISS) P43427 (/ISS) P43427 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
5 P22732 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS)
Hexose transmembrane transport GO:0008645
The process in which hexose is transported across a membrane. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.
4 P11168 (/TAS) Q6PXP3 (/TAS) Q9BYW1 (/TAS) Q9NRM0 (/TAS)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
4 P11168 (/IDA) P22732 (/IDA) P43427 (/IDA) P43427 (/IDA)
Glucose import in response to insulin stimulus GO:0044381
The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.
4 P14672 (/ISS) P19357 (/ISS) Q27994 (/ISS) Q27994 (/ISS)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
4 P14672 (/ISS) Q27994 (/ISS) Q27994 (/ISS) Q9XSC2 (/ISS)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
4 P11168 (/TAS) P14142 (/TAS) P14672 (/TAS) P22732 (/TAS)
Fructose import across plasma membrane GO:1990539
The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
4 P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
3 P11168 (/TAS) P14672 (/TAS) P22732 (/TAS)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
3 P12336 (/IEP) P43427 (/IEP) P43427 (/IEP)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
3 P19357 (/ISS) Q27994 (/ISS) Q27994 (/ISS)
Glucose import GO:0046323
The directed movement of the hexose monosaccharide glucose into a cell or organelle.
3 B0UY92 (/IMP) P19357 (/IMP) Q102R8 (/IMP)
Dehydroascorbic acid transport GO:0070837
The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
3 P11168 (/IDA) P12336 (/IDA) P14246 (/IDA)
Cellular response to fructose stimulus GO:0071332
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
3 P43427 (/IDA) P43427 (/IDA) Q9WV38 (/IDA)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
3 P14142 (/ISO) P14246 (/ISO) Q9WV38 (/ISO)
Fructose import across plasma membrane GO:1990539
The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
3 P22732 (/IDA) P43427 (/IDA) P43427 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
2 B0UY92 (/IMP) Q102R8 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 B0UY92 (/IMP) Q102R8 (/IMP)
Hexose transmembrane transport GO:0008645
The process in which hexose is transported across a membrane. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.
2 B0UY92 (/IDA) Q102R8 (/IDA)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
2 P12336 (/ISS) P14246 (/ISS)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
2 P14142 (/IDA) P14672 (/IDA)
Glucose import in response to insulin stimulus GO:0044381
The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.
2 P14142 (/IDA) P19357 (/IDA)
Glucose import GO:0046323
The directed movement of the hexose monosaccharide glucose into a cell or organelle.
2 B0UY92 (/IDA) Q102R8 (/IDA)
Intestinal hexose absorption GO:0106001
Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.
2 P11168 (/TAS) P22732 (/TAS)
Regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044
The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
1 Q9WV38 (/IMP)
Carbohydrate transport GO:0008643
The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
1 P14246 (/TAS)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P12336 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 Q9WV38 (/IMP)
Carbohydrate utilization GO:0009758
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.
1 P12336 (/IMP)
Carbohydrate utilization GO:0009758
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.
1 P14246 (/ISO)
Amylopectin biosynthetic process GO:0010021
The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.
1 P14142 (/IDA)
Urate transport GO:0015747
The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q3T9X0 (/IDA)
Urate transport GO:0015747
The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q3T9X0 (/IMP)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 Q9WV38 (/ISO)
Fructose transmembrane transport GO:0015755
The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
1 P22732 (/TAS)
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
1 P14246 (/TAS)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P19357 (/IEP)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P14142 (/ISO)
Response to tumor necrosis factor GO:0034612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
1 Q9DFV2 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 P14672 (/IDA)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 Q8IRI6 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 P14142 (/ISO)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
1 P22732 (/TAS)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P12336 (/IEP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 P19357 (/IEP)
Glucose import GO:0046323
The directed movement of the hexose monosaccharide glucose into a cell or organelle.
1 P14142 (/ISO)
Glucose import GO:0046323
The directed movement of the hexose monosaccharide glucose into a cell or organelle.
1 P14672 (/NAS)
Urate metabolic process GO:0046415
The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
1 Q9NRM0 (/IMP)
Urate metabolic process GO:0046415
The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
1 Q3T9X0 (/ISO)
Regulation of insulin secretion GO:0050796
Any process that modulates the frequency, rate or extent of the regulated release of insulin.
1 P11168 (/TAS)
Brown fat cell differentiation GO:0050873
The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
1 P14142 (/IDA)
Dehydroascorbic acid transport GO:0070837
The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
1 P14246 (/ISO)
Cellular response to fructose stimulus GO:0071332
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 Q9WV38 (/ISO)
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
1 P14142 (/IDA)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P19357 (/IDA)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P14142 (/ISO)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 P14142 (/IDA)
Positive regulation of peptide hormone secretion GO:0090277
Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
1 Q8IRI6 (/IMP)
Regulation of synaptic vesicle budding from presynaptic endocytic zone membrane GO:0098694
Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.
1 P19357 (/IDA)
Regulation of synaptic vesicle budding from presynaptic endocytic zone membrane GO:0098694
Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.
1 P19357 (/IMP)
Regulation of synaptic vesicle budding from presynaptic endocytic zone membrane GO:0098694
Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.
1 P14142 (/ISO)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
1 P12336 (/IEP)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
1 P19357 (/IMP)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
1 Q9NRM0 (/NAS)
Fructose import across plasma membrane GO:1990539
The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
1 Q9WV38 (/IMP)
Fructose import across plasma membrane GO:1990539
The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
1 Q9WV38 (/ISO)

There are 72 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 P11168 (/IDA) P12336 (/IDA) P14142 (/IDA) P14246 (/IDA) P14672 (/IDA) P19357 (/IDA) P22732 (/IDA) Q3T9X0 (/IDA) Q6PXP3 (/IDA) Q9BYW1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 A4ZYQ5 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q27994 (/ISS) Q27994 (/ISS) Q5RET7 (/ISS) Q863Y9 (/ISS) Q8WMN1 (/ISS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
9 P22732 (/ISS) P43427 (/ISS) P43427 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q5RET7 (/ISS) Q863Y9 (/ISS) Q8WMN1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P11168 (/TAS) P14142 (/TAS) P14246 (/TAS) P14672 (/TAS) P22732 (/TAS) Q6PXP3 (/TAS) Q9BYW1 (/TAS) Q9NRM0 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS) Q9WV38 (/ISS) Q9XSC2 (/ISS)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
6 P22732 (/ISS) P46408 (/ISS) P58353 (/ISS) P58353 (/ISS) Q863Y9 (/ISS) Q9WV38 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 P14142 (/IDA) P22732 (/IDA) P43427 (/IDA) P43427 (/IDA)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
4 P14672 (/ISS) P19357 (/ISS) Q27994 (/ISS) Q27994 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 P14142 (/IDA) P19357 (/IDA) P43427 (/IDA) P43427 (/IDA)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
4 P14672 (/ISS) P19357 (/ISS) Q27994 (/ISS) Q27994 (/ISS)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
4 P14142 (/IDA) P19357 (/IDA) P43427 (/IDA) P43427 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P12336 (/IDA) P14246 (/IDA) P19357 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
3 P12336 (/IDA) P14142 (/IDA) P19357 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P12336 (/IDA) P14142 (/IDA) P19357 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
3 P14246 (/IDA) Q3T9X0 (/IDA) Q9WV38 (/IDA)
Insulin-responsive compartment GO:0032593
A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
3 P14142 (/IDA) P14672 (/IDA) P19357 (/IDA)
Insulin-responsive compartment GO:0032593
A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
3 P14672 (/ISS) Q27994 (/ISS) Q27994 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 P14142 (/IDA) P14672 (/IDA) P19357 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P14142 (/ISO) P14246 (/ISO)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
2 P14142 (/ISO) P14246 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P14142 (/ISO) P14246 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P14142 (/ISO) P14246 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P11168 (/TAS) P14672 (/TAS)
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
2 P12336 (/IDA) P14246 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P14142 (/ISO) Q9WV38 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P11168 (/TAS) P14672 (/TAS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 P12336 (/IDA) Q3T9X0 (/IDA)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
2 P14142 (/ISO) Q9WV38 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q27994 (/ISS) Q27994 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9BYW1 (/IDA)
Multivesicular body GO:0005771
A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
1 P19357 (/IDA)
Multivesicular body GO:0005771
A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
1 P14142 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9WV38 (/ISO)
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
1 P14246 (/ISO)
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
1 P19357 (/IDA)
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
1 P14142 (/ISO)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
1 P14246 (/IDA)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P14672 (/IDA)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P14142 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P19357 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q9DFV2 (/IMP)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P14142 (/ISO)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
1 P14142 (/IDA)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
1 P14672 (/IDA)
Vesicle membrane GO:0012506
The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
1 P14142 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P14142 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9XSC2 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9NRM0 (/NAS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 P14246 (/ISO)
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
1 P19357 (/IDA)
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
1 P14142 (/ISO)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
1 Q9BYW1 (/IDA)
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
1 P14672 (/IDA)
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
1 P14142 (/ISO)
Trans-Golgi network transport vesicle GO:0030140
A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
1 P14142 (/IDA)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 P19357 (/IDA)
T-tubule GO:0030315
Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
1 P14142 (/ISO)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
1 P14142 (/IDA)
Cytoplasmic vesicle membrane GO:0030659
The lipid bilayer surrounding a cytoplasmic vesicle.
1 P14142 (/TAS)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 P12336 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 P14246 (/ISO)
Insulin-responsive compartment GO:0032593
A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
1 P14142 (/ISO)
Specific granule membrane GO:0035579
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
1 P22732 (/TAS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P19357 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 P14142 (/ISO)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
1 P14142 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 P14142 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P22732 (/HDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P14142 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 P19357 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 P19357 (/IMP)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 P14142 (/ISO)