The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Sugar transport protein 13

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Monosaccharide transmembrane transporter activity GO:0015145
Enables the transfer of a monosaccharide from one side of a membrane to the other.
6 Q39228 (/IDA) Q39228 (/IDA) Q9LNV3 (/IDA) Q9LNV3 (/IDA) Q9SBA7 (/IDA) Q9SFG0 (/IDA)
Hexose:proton symporter activity GO:0009679
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).
4 Q94AZ2 (/IDA) Q94AZ2 (/IDA) Q9LT15 (/IDA) Q9LT15 (/IDA)
Monosaccharide transmembrane transporter activity GO:0015145
Enables the transfer of a monosaccharide from one side of a membrane to the other.
4 P23586 (/IMP) P23586 (/IMP) Q94AZ2 (/IMP) Q94AZ2 (/IMP)
Galactose transmembrane transporter activity GO:0005354
Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
2 Q9LT15 (/IDA) Q9LT15 (/IDA)
High-affinity glucose:proton symporter activity GO:0005358
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2 Q94AZ2 (/IDA) Q94AZ2 (/IDA)
Sucrose:proton symporter activity GO:0008506
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).
2 Q39228 (/IDA) Q39228 (/IDA)
Mannose transmembrane transporter activity GO:0015578
Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
2 Q9LT15 (/IDA) Q9LT15 (/IDA)
Arabinose transmembrane transporter activity GO:0042900
Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other.
2 O04249 (/IDA) O04249 (/IDA)
D-glucose:proton symporter activity GO:0055055
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose.
2 Q9LT15 (/IDA) Q9LT15 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Monosaccharide transmembrane transport GO:0015749
The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
4 P23586 (/IMP) P23586 (/IMP) Q94AZ2 (/IMP) Q94AZ2 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 Q94AZ2 (/IEP) Q94AZ2 (/IEP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
2 Q9LNV3 (/TAS) Q9LNV3 (/TAS)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
2 Q94AZ2 (/IEP) Q94AZ2 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
2 Q94AZ2 (/IEP) Q94AZ2 (/IEP)
Monosaccharide transmembrane transport GO:0015749
The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
2 Q9LNV3 (/TAS) Q9LNV3 (/TAS)
Sucrose transport GO:0015770
The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.
2 Q39228 (/TAS) Q39228 (/TAS)
L-arabinose transmembrane transport GO:0042882
The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.
2 O04249 (/IDA) O04249 (/IDA)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 Q9LT15 (/IEP) Q9LT15 (/IEP)
Monosaccharide transmembrane transport GO:0015749
The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
1 Q9SBA7 (/IDA)
Carbohydrate transmembrane transport GO:0034219
The process in which a carbohydrate is transported across a membrane.
1 Q9SFG0 (/TAS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 O04249 (/IDA) O04249 (/IDA) P23586 (/IDA) P23586 (/IDA) Q39228 (/IDA) Q39228 (/IDA) Q8GW61 (/IDA) Q94AZ2 (/IDA) Q94AZ2 (/IDA) Q9LT15 (/IDA)
(2 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 Q39228 (/ISS) Q39228 (/ISS) Q9LNV3 (/ISS) Q9LNV3 (/ISS)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
4 P23586 (/IDA) P23586 (/IDA) Q94AZ2 (/IDA) Q94AZ2 (/IDA)
Pollen tube GO:0090406
A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
4 O04249 (/IDA) O04249 (/IDA) Q9FMX3 (/IDA) Q9SBA7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P23586 (/IDA) P23586 (/IDA)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 P23586 (/IDA) P23586 (/IDA)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
2 O04249 (/IDA) O04249 (/IDA)