The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 189: thiamine transporter 1 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
5 O60779 (/IDA) O60779 (/IDA) O60779 (/IDA) O60779 (/IDA) Q9EQN9 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 O60779 (/IPI) O60779 (/IPI) O60779 (/IPI) O60779 (/IPI)
Folic acid transmembrane transporter activity GO:0008517
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
4 O60779 (/NAS) O60779 (/NAS) O60779 (/NAS) O60779 (/NAS)
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
4 O60779 (/ISS) O60779 (/ISS) O60779 (/ISS) O60779 (/ISS)
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
4 O60779 (/TAS) O60779 (/TAS) O60779 (/TAS) O60779 (/TAS)
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
1 Q9EQN9 (/IMP)
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
1 Q9EQN9 (/ISO)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiamine transport GO:0015888
The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
4 O60779 (/NAS) O60779 (/NAS) O60779 (/NAS) O60779 (/NAS)
Thiamine-containing compound metabolic process GO:0042723
The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
4 O60779 (/TAS) O60779 (/TAS) O60779 (/TAS) O60779 (/TAS)
Thiamine transmembrane transport GO:0071934
The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
4 O60779 (/ISS) O60779 (/ISS) O60779 (/ISS) O60779 (/ISS)
Thiamine transport GO:0015888
The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
1 Q9EQN9 (/IDA)
Thiamine transmembrane transport GO:0071934
The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
1 Q9EQN9 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 O60779 (/IDA) O60779 (/IDA) O60779 (/IDA) O60779 (/IDA) Q9EQN9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O60779 (/TAS) O60779 (/TAS) O60779 (/TAS) O60779 (/TAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 O60779 (/NAS) O60779 (/NAS) O60779 (/NAS) O60779 (/NAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9EQN9 (/IC)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9EQN9 (/ISO)