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CATH Superfamily 1.20.1250.20

MFS general substrate transporter like domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Nucleoside permease NupG

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytidine transmembrane transporter activity GO:0015212
Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.
 108 P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP)
(98 more)
Uridine transmembrane transporter activity GO:0015213
Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
 108 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(98 more)
Uridine transmembrane transporter activity GO:0015213
Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
 108 P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP)
(98 more)
Pyrimidine nucleoside transmembrane transporter activity GO:0015214
Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.
 108 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(98 more)
Nucleoside transmembrane transporter activity GO:0005337
Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.
 15 P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA)
(5 more)
Xanthosine transmembrane transporter activity GO:0015553
Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.
 15 P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS)
(5 more)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Purine nucleoside transmembrane transport GO:0015860
The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.
 108 P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP)
(98 more)
Uridine transport GO:0015862
The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 108 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(98 more)
Pyrimidine nucleoside transport GO:0015864
The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 108 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(98 more)
Adenosine transport GO:0032238
The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 108 P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP) P0AFF4 (/IMP)
(98 more)
Nucleoside transport GO:0015858
The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 15 P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA) P45562 (/ISA)
(5 more)
Nucleobase-containing small molecule metabolic process GO:0055086
The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
 15 P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP) P45562 (/IMP)
(5 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 123 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(113 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 108 P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA) P0AFF4 (/IDA)
(98 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 15 P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA) P45562 (/IDA)
(5 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 15 P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS) P45562 (/ISS)
(5 more)