The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MFS general substrate transporter like domains
".
FunFam 1045: Solute carrier family 17 (sodium phosphate), membe...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium:phosphate symporter activity GO:0005436
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).
|
1 | Q5SZ93 (/ISS) |
|
Voltage-gated anion channel activity GO:0008308
Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q5SZ93 (/ISO) |
|
Voltage-gated anion channel activity GO:0008308
Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q5SZ93 (/ISS) |
|
Organic anion transmembrane transporter activity GO:0008514
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
|
1 | Q5SZ93 (/ISO) |
|
Organic anion transmembrane transporter activity GO:0008514
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
|
1 | Q5SZ93 (/ISS) |
|
Urate transmembrane transporter activity GO:0015143
Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
|
1 | Q5SZ93 (/ISO) |
|
Urate transmembrane transporter activity GO:0015143
Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
|
1 | Q5SZ93 (/ISS) |
|
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
|
1 | Q5SZ93 (/ISO) |
|
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
|
1 | Q5SZ93 (/ISS) |
|
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | Q5SZ93 (/ISO) |
|
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | Q5SZ93 (/ISS) |
|
Xenobiotic transmembrane transporter activity GO:0042910
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
|
1 | Q5SZ93 (/ISO) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5SZ93 (/ISS) |
|
Phosphate ion transport GO:0006817
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5SZ93 (/ISS) |
|
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
|
1 | Q5SZ93 (/ISO) |
|
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
|
1 | Q5SZ93 (/ISS) |
|
Urate transport GO:0015747
The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5SZ93 (/ISO) |
|
Urate transport GO:0015747
The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5SZ93 (/ISS) |
|
Urate metabolic process GO:0046415
The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
|
1 | Q5SZ93 (/ISO) |
|
Urate metabolic process GO:0046415
The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
|
1 | Q5SZ93 (/ISS) |
|
Xenobiotic detoxification by transmembrane export across the plasma membrane GO:1990961
A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.
|
1 | Q5SZ93 (/ISO) |
|
Xenobiotic detoxification by transmembrane export across the plasma membrane GO:1990961
A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.
|
1 | Q5SZ93 (/ISS) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q5SZ93 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q5SZ93 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q5SZ93 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q5SZ93 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q5SZ93 (/ISS) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q5SZ93 (/ISO) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q5SZ93 (/ISS) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | Q5SZ93 (/ISS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q5SZ93 (/ISO) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q5SZ93 (/ISS) |