CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 34: Interleukin-5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Interleukin-5 receptor binding GO:0005137
Interacting selectively and non-covalently with the interleukin-5 receptor.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P05113 (/IPI) P05113 (/IPI) P05113 (/IPI) P05113 (/IPI) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
3 | P04401 (/IDA) P04401 (/IDA) Q08125 (/IDA) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Interleukin-5 receptor binding GO:0005137
Interacting selectively and non-covalently with the interleukin-5 receptor.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | Q08125 (/IMP) |
|
Interleukin-5 receptor binding GO:0005137
Interacting selectively and non-covalently with the interleukin-5 receptor.
|
1 | Q08125 (/IDA) |
|
Interleukin-5 receptor binding GO:0005137
Interacting selectively and non-covalently with the interleukin-5 receptor.
|
1 | Q08125 (/IMP) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
4 | P05113 (/ISS) P05113 (/ISS) P05113 (/ISS) P05113 (/ISS) |
|
Positive regulation of podosome assembly GO:0071803
Any process that activates or increases the rate or extent of podosome assembly.
|
4 | P05113 (/IDA) P05113 (/IDA) P05113 (/IDA) P05113 (/IDA) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Positive regulation of eosinophil differentiation GO:0045645
Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P04401 (/IDA) P04401 (/IDA) |
|
Positive regulation of receptor signaling pathway via JAK-STAT GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
2 | P04401 (/IDA) P04401 (/IDA) |
|
Positive regulation of immunoglobulin secretion GO:0051024
Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell.
|
2 | P04401 (/IGI) P04401 (/IGI) |
|
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
2 | P04401 (/IDA) P04401 (/IDA) |
|
Positive regulation of podosome assembly GO:0071803
Any process that activates or increases the rate or extent of podosome assembly.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | Q08125 (/IEP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q08125 (/IDA) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q08125 (/IDA) |
|
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q08125 (/IMP) |
|
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
1 | Q08125 (/IDA) |
|
Positive regulation of eosinophil differentiation GO:0045645
Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
|
1 | Q08125 (/IDA) |
|
Positive regulation of receptor signaling pathway via JAK-STAT GO:0046427
Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
|
1 | Q08125 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | P05113 (/IDA) P05113 (/IDA) P05113 (/IDA) P05113 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) P05113 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | P04401 (/IDA) P04401 (/IDA) Q08125 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P04401 (/ISO) P04401 (/ISO) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P04401 (/ISO) P04401 (/ISO) |