The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Pex19, mPTS binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Putative peroxisomal biogenesis factor 19

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P34453 (/IPI) P40855 (/IPI) P40855 (/IPI) P40855 (/IPI) P40855 (/IPI) Q8VCI5 (/IPI) Q9QYU1 (/IPI)
Peroxisome membrane class-1 targeting sequence binding GO:0036105
Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
4 P40855 (/IPI) P40855 (/IPI) P40855 (/IPI) P40855 (/IPI)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
4 P40855 (/IPI) P40855 (/IPI) P40855 (/IPI) P40855 (/IPI)
Peroxisome membrane class-1 targeting sequence binding GO:0036105
Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
1 Q8VCI5 (/ISO)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q8VCI5 (/ISO)
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
1 Q8VCI5 (/ISO)

There are 26 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
4 P40855 (/IMP) P40855 (/IMP) P40855 (/IMP) P40855 (/IMP)
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
4 P40855 (/IMP) P40855 (/IMP) P40855 (/IMP) P40855 (/IMP)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
4 P40855 (/NAS) P40855 (/NAS) P40855 (/NAS) P40855 (/NAS)
Peroxisome membrane biogenesis GO:0016557
The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
4 P40855 (/IMP) P40855 (/IMP) P40855 (/IMP) P40855 (/IMP)
Protein import into peroxisome membrane GO:0045046
The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
4 P40855 (/TAS) P40855 (/TAS) P40855 (/TAS) P40855 (/TAS)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Establishment of protein localization to peroxisome GO:0072663
The directed movement of a protein to a specific location in a peroxisome.
4 P40855 (/IMP) P40855 (/IMP) P40855 (/IMP) P40855 (/IMP)
Negative regulation of lipid binding GO:1900131
Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
1 P34453 (/IMP)
Protein targeting to peroxisome GO:0006625
The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
1 Q8VCI5 (/ISO)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
1 Q8VCI5 (/ISO)
Peroxisome membrane biogenesis GO:0016557
The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.
1 Q8VCI5 (/ISO)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
1 Q8VCI5 (/ISO)
Protein import into peroxisome membrane GO:0045046
The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.
1 Q8VCI5 (/ISO)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q8VCI5 (/ISO)
Chaperone-mediated protein folding GO:0061077
The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
1 Q8VCI5 (/ISO)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
1 Q8VCI5 (/ISO)
Establishment of protein localization to peroxisome GO:0072663
The directed movement of a protein to a specific location in a peroxisome.
1 Q8VCI5 (/ISO)
Negative regulation of lipid binding GO:1900131
Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
1 Q8VCI5 (/ISO)

There are 25 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
10 A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) G3V3G9 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) Q5QNY5 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
10 A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) A0A0S2Z497 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) Q5QNY5 (/IDA) Q9QYU1 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P40855 (/ISS) P40855 (/ISS) P40855 (/ISS) P40855 (/ISS) Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) Q9QYU1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 G3V3G9 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
4 P40855 (/ISS) P40855 (/ISS) P40855 (/ISS) P40855 (/ISS)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
4 P40855 (/HDA) P40855 (/HDA) P40855 (/HDA) P40855 (/HDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P40855 (/TAS) P40855 (/TAS) P40855 (/TAS) P40855 (/TAS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 Q3SZD1 (/ISS) Q5R7U2 (/ISS) Q60415 (/ISS) Q60415 (/ISS)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
4 P40855 (/ISS) P40855 (/ISS) P40855 (/ISS) P40855 (/ISS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
4 P40855 (/IDA) P40855 (/IDA) P40855 (/IDA) P40855 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8VCI5 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8VCI5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8VCI5 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 G3V3G9 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 Q8VCI5 (/ISO)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
1 Q8VCI5 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8VCI5 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8VCI5 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q9QYU1 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q8VCI5 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q8VCI5 (/ISO)