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CATH Superfamily 1.20.120.530

GntR ligand-binding domain-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GntR ligand-binding domain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Pyruvate dehydrogenase complex transcriptional rep...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 189 P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS)
(179 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 176 P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA)
(166 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 176 P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA)
(166 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 176 P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA)
(166 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 176 P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS)
(166 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 176 P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA)
(166 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
 176 P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS) P0ACL9 (/ISS)
(166 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
 13 Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS) Q9KPF3 (/ISS)
(3 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
 176 P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA) P0ACL9 (/IDA)
(166 more)