The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Voltage-gated potassium channels. Chain C
".
FunFam 52: polycystic kidney disease 2-like 1 protein isoform...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 24 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
2 | A2A259 (/IDA) Q9P0L9 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | A2A259 (/IDA) Q9P0L9 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | A2A259 (/IPI) Q9P0L9 (/IPI) |
|
Calcium activated cation channel activity GO:0005227
Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | Q9P0L9 (/IDA) |
|
Calcium activated cation channel activity GO:0005227
Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | A2A259 (/ISO) |
|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | A2A259 (/IPI) |
|
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
1 | A2A259 (/ISO) |
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | Q9P0L9 (/IDA) |
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | A2A259 (/IMP) |
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | A2A259 (/ISO) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | Q9P0L9 (/IDA) |
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | A2A259 (/ISO) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | A2A259 (/ISO) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9P0L9 (/ISS) |
|
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
|
1 | Q9P0L9 (/IPI) |
|
Cytoskeletal protein binding GO:0008092
Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
|
1 | A2A259 (/ISO) |
|
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
|
1 | Q9P0L9 (/IDA) |
|
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
|
1 | A2A259 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | A2A259 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9P0L9 (/ISS) |
|
Muscle alpha-actinin binding GO:0051371
Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
|
1 | Q9P0L9 (/IPI) |
|
Muscle alpha-actinin binding GO:0051371
Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
|
1 | A2A259 (/ISO) |
|
Alpha-actinin binding GO:0051393
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
|
1 | Q9P0L9 (/IPI) |
|
Alpha-actinin binding GO:0051393
Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
|
1 | A2A259 (/ISO) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Inorganic cation transmembrane transport GO:0098662
A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
2 | A2A259 (/IDA) Q9P0L9 (/IDA) |
|
Detection of chemical stimulus involved in sensory perception of sour taste GO:0001581
The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
|
1 | A2A259 (/IDA) |
|
Detection of chemical stimulus involved in sensory perception of sour taste GO:0001581
The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
|
1 | Q9P0L9 (/ISS) |
|
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | A2A259 (/IDA) |
|
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9P0L9 (/ISS) |
|
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
|
1 | A2A259 (/IMP) |
|
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
|
1 | Q9P0L9 (/ISS) |
|
Response to water GO:0009415
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
|
1 | A2A259 (/IMP) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q9P0L9 (/IDA) |
|
Sodium ion transmembrane transport GO:0035725
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | A2A259 (/ISO) |
|
Detection of chemical stimulus involved in sensory perception of taste GO:0050912
The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.
|
1 | A2A259 (/IMP) |
|
Detection of chemical stimulus involved in sensory perception of taste GO:0050912
The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.
|
1 | Q9P0L9 (/ISS) |
|
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
1 | Q9P0L9 (/IMP) |
|
Sensory perception of sour taste GO:0050915
The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
|
1 | A2A259 (/ISO) |
|
Protein tetramerization GO:0051262
The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
|
1 | A2A259 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | Q9P0L9 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | A2A259 (/ISO) |
|
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | A2A259 (/IDA) |
|
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | A2A259 (/IDA) |
|
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
1 | Q9P0L9 (/ISS) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | Q9P0L9 (/IDA) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | A2A259 (/ISO) |
|
Inorganic cation transmembrane transport GO:0098662
A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | A2A259 (/ISO) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
|
2 | A2A259 (/IDA) Q9P0L9 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | A2A259 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9P0L9 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9P0L9 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9P0L9 (/IMP) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | A2A259 (/IPI) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | A2A259 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | A2A259 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9P0L9 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | A2A259 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9P0L9 (/NAS) |
|
Cation channel complex GO:0034703
An ion channel complex through which cations pass.
|
1 | A2A259 (/IDA) |
|
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
|
1 | A2A259 (/IMP) |
|
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
|
1 | A2A259 (/ISO) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q9P0L9 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | A2A259 (/ISO) |
|
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | A2A259 (/IDA) |
|
Receptor complex GO:0043235
Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q9P0L9 (/ISS) |
|
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
|
1 | Q9P0L9 (/IDA) |
|
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
|
1 | A2A259 (/ISO) |
|
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
|
1 | A2A259 (/ISS) |