The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Nucleotidyltransferases domain 2
".
FunFam 17: Polarisome protein, putative
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAP-kinase scaffold activity GO:0005078
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
|
1 | P23201 (/IDA) |
|
MAP-kinase scaffold activity GO:0005078
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
|
1 | P23201 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P23201 (/IPI) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular bud site selection GO:0000282
The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
|
1 | A0A1D8PFH4 (/IMP) |
|
Budding cell apical bud growth GO:0007118
Growth at the tip of a bud, in a cell that reproduces by budding.
|
1 | P23201 (/IGI) |
|
Budding cell apical bud growth GO:0007118
Growth at the tip of a bud, in a cell that reproduces by budding.
|
1 | P23201 (/IMP) |
|
Bipolar cellular bud site selection GO:0007121
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
|
1 | P23201 (/IMP) |
|
Pseudohyphal growth GO:0007124
A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
|
1 | P23201 (/IMP) |
|
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | A0A1D8PFH4 (/IMP) |
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
|
1 | A0A1D8PFH4 (/IMP) |
|
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
|
1 | P23201 (/IMP) |
|
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | A0A1D8PFH4 (/IMP) |
|
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
|
1 | A0A1D8PFH4 (/IMP) |
|
Establishment or maintenance of cytoskeleton polarity GO:0030952
Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.
|
1 | A0A1D8PFH4 (/IMP) |
|
Mating projection assembly GO:0031382
The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.
|
1 | P23201 (/IGI) |
|
Regulation of initiation of mating projection growth GO:0031384
Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.
|
1 | P23201 (/IMP) |
|
Regulation of termination of mating projection growth GO:0031385
Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.
|
1 | P23201 (/IMP) |
|
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
|
1 | P23201 (/IMP) |
|
Invasive filamentous growth GO:0036267
The growth of colonies in filamentous chains of cells into a substrate.
|
1 | P23201 (/IGI) |
|
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | A0A1D8PFH4 (/IMP) |
|
Regulation of cellular protein localization GO:1903827
Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
|
1 | P23201 (/IMP) |
|
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
|
1 | P23201 (/IGI) |
|
Positive regulation of actin cytoskeleton reorganization GO:2000251
Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
|
1 | P23201 (/IMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Incipient cellular bud site GO:0000131
The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
|
2 | A0A1D8PFH4 (/IDA) P23201 (/IDA) |
|
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
2 | A0A1D8PFH4 (/IDA) P23201 (/IDA) |
|
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
|
2 | A0A1D8PFH4 (/IDA) P23201 (/IDA) |
|
Polarisome GO:0000133
Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.
|
1 | P23201 (/IDA) |
|
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
|
1 | A0A1D8PFH4 (/IDA) |
|
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
1 | P23201 (/IDA) |
|
Site of polarized growth GO:0030427
Any part of a cell where non-isotropic growth takes place.
|
1 | A0A1D8PFH4 (/IDA) |
|
Cellular bud neck polarisome GO:0031560
Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
|
1 | A0A1D8PFH4 (/IDA) |
|
Cellular bud tip polarisome GO:0031561
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
|
1 | A0A1D8PFH4 (/IDA) |
|
Hyphal tip polarisome GO:0031562
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
|
1 | A0A1D8PFH4 (/IDA) |
|
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
1 | P23201 (/IDA) |