The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ERV/ALR sulfhydryl oxidase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Sulfhydryl oxidase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiol oxidase activity GO:0016972
Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
10 Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q8GXX0 (/IDA)
Protein disulfide isomerase activity GO:0003756
Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
3 G4MNC0 (/ISS) G4MNC0 (/ISS) G4MNC0 (/ISS)
Thiol oxidase activity GO:0016972
Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
3 G4MNC0 (/ISS) G4MNC0 (/ISS) G4MNC0 (/ISS)
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
1 C0PVB3 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8GXX0 (/IPI)
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
1 Q8GXX0 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
9 Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI) Q12284 (/IGI)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
3 C0PVB3 (/IEP) Q7KUU5 (/IEP) Q8SX43 (/IEP)
Tissue regeneration GO:0042246
The regrowth of lost or destroyed tissues.
3 C0PVB3 (/IMP) Q7KUU5 (/IMP) Q8SX43 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
9 Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
9 Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA) Q12284 (/HDA)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
9 Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA) Q12284 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8GXX0 (/IDA)