The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alpha-catenin/vinculin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Catenin alpha 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q65CL1 (/IPI) Q9UI47 (/IPI)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
2 Q65CL1 (/TAS) Q9UI47 (/TAS)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q9UI47 (/IPI)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q65CL1 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication GO:0086073
The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
1 Q9UI47 (/IMP)
Bundle of His cell-Purkinje myocyte adhesion involved in cell communication GO:0086073
The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
1 Q65CL1 (/ISO)
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
1 Q9UI47 (/IMP)
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
1 Q65CL1 (/ISO)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
1 Q65CL1 (/IDA)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
1 Q9UI47 (/IPI)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
1 Q65CL1 (/ISO)
Regulation of ventricular cardiac muscle cell action potential GO:0098911
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
1 Q9UI47 (/IMP)
Regulation of ventricular cardiac muscle cell action potential GO:0098911
Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
1 Q65CL1 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fascia adherens GO:0005916
A cell-cell adherens junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.
2 Q65CL1 (/IDA) Q9UI47 (/IDA)
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
1 Q65CL1 (/IDA)
Fascia adherens GO:0005916
A cell-cell adherens junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.
1 Q65CL1 (/ISO)
Fascia adherens GO:0005916
A cell-cell adherens junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.
1 Q65CL1 (/ISS)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
1 Q65CL1 (/IDA)