The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Small t-antigen, unique domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Small t-antigen, unique domain

The small t-antigen (ST) is structurally formed of an N-terminal J domain and a C-terminal unique domain.

This superfamily represents the unique domain that contains two zinc-binding motifs. It comprises four helices and it is rich in Cys residues, six of which are organised into two CxCxxC clusters and bind two zinc ions, providing structural stability to ST. PMID:17608567

This domain represents a conserved region in papovavirus small and middle T-antigens. It is found as the N-terminal domain in the small T-antigen, and is centrally located in the middle T-antigen PMID:9557685.

PFAM:PF02380,INTERPRO:IPR003354

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
112 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 3
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO: 1
Taxonomy
Unique Species: 112