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CATH Superfamily 1.20.120.1760

CDP-alcohol phosphotransferase transmembrane (TM) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 42: Bifunctional IPC transferase and DIPP synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1L-myo-inositol 1-phosphate cytidylyltransferase. [EC: 2.7.7.74]
CTP + 1L-myo-inositol 1-phosphate = diphosphate + CDP-1L-myo-inositol.
  • In many organisms this activity is catalyzed by a bifunctional enzyme.
  • The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 (CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase) is absolutely specific for CTP and 1L-myo-inositol 1-phosphate.
  • The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments.
  • In many organisms this activity is catalyzed by a bifunctional enzyme.
  • The cytidylyltransferase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 is absolutely specific for CTP and 1L-myo- inositol 1-phosphate.
  • The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate, a widespread organic solute in microorganisms adapted to hot environments.
 5 O29976 O67379 Q1AWQ0 Q5JDA9 Q8U1Z6
CDP-L-myo-inositol myo-inositolphosphotransferase. [EC: 2.7.8.34]
CDP-1L-myo-inositol + 1L-myo-inositol 1-phosphate = CMP + bis(1L-myo- inositol) 3,1'-phosphate 1-phosphate.
  • In many organisms this activity is catalyzed by a bifunctional enzyme.
  • The di-myo-inositol-1,3'-phosphate-1'-phosphate synthase domain of the bifunctional EC 2.7.7.74/EC 2.7.8.34 uses only 1L-myo-inositol 1-phosphate as an alcohol acceptor, but CDP-glycerol, as well as CDP- 1L-myo-inositol and CDP-D-myo-inositol, are recognized as alcohol donors.
  • The enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3- phosphate, a widespread organic solute in microorganisms adapted to hot environments.
 5 O29976 O67379 Q1AWQ0 Q5JDA9 Q8U1Z6