The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 35: C-C chemokine receptor type 6
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 28 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
7 | O00574 (/TAS) O00574 (/TAS) P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P47774 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | O54689 (/IPI) O54689 (/IPI) P47774 (/IPI) P51684 (/IPI) P51684 (/IPI) Q9NPB9 (/IPI) Q9WUT7 (/IPI) |
|
Chemokine receptor activity GO:0004950
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
6 | P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) Q9NPB9 (/TAS) |
|
C-C chemokine receptor activity GO:0016493
Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
5 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) Q9WUT7 (/IDA) |
|
C-C chemokine receptor activity GO:0016493
Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
C-C chemokine binding GO:0019957
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
4 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) |
|
Chemokine (C-C motif) ligand 19 binding GO:0035757
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19.
|
4 | P32248 (/IPI) P32248 (/IPI) P32248 (/IPI) P32248 (/IPI) |
|
Chemokine (C-C motif) ligand 21 binding GO:0035758
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21.
|
4 | P32248 (/IPI) P32248 (/IPI) P32248 (/IPI) P32248 (/IPI) |
|
C-C motif chemokine 19 receptor activity GO:0038117
Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
4 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) |
|
C-C motif chemokine 21 receptor activity GO:0038121
Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
4 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) |
|
C-C chemokine receptor activity GO:0016493
Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
3 | P47774 (/IMP) P51684 (/IMP) P51684 (/IMP) |
|
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
|
2 | A5PLI3 (/IMP) F1QLM4 (/IMP) |
|
Chemokine receptor activity GO:0004950
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
2 | P35350 (/ISS) Q924I3 (/ISS) |
|
Coreceptor activity GO:0015026
Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
|
2 | O00574 (/TAS) O00574 (/TAS) |
|
C-C chemokine receptor activity GO:0016493
Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
C-C chemokine binding GO:0019957
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
2 | P51684 (/IMP) P51684 (/IMP) |
|
C-C chemokine binding GO:0019957
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
2 | P51684 (/TAS) P51684 (/TAS) |
|
Chemokine receptor activity GO:0004950
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
1 | Q9NPB9 (/IDA) |
|
Chemokine receptor activity GO:0004950
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
1 | Q924I3 (/ISO) |
|
C-X-C chemokine receptor activity GO:0016494
Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.
|
1 | Q9EQ16 (/IDA) |
|
C-X-C chemokine binding GO:0019958
Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
|
1 | Q9EQ16 (/IPI) |
|
Chemokine (C-C motif) ligand 19 binding GO:0035757
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19.
|
1 | P47774 (/ISO) |
|
Chemokine (C-C motif) ligand 19 binding GO:0035757
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19.
|
1 | P47774 (/ISS) |
|
Chemokine (C-C motif) ligand 21 binding GO:0035758
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21.
|
1 | P47774 (/ISO) |
|
Chemokine (C-C motif) ligand 21 binding GO:0035758
Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21.
|
1 | P47774 (/ISS) |
|
C-C motif chemokine 19 receptor activity GO:0038117
Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | P47774 (/ISO) |
|
C-C motif chemokine 21 receptor activity GO:0038121
Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | P47774 (/ISO) |
There are 131 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
12 |
O00574 (/TAS)
O00574 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P51684 (/TAS)
P51684 (/TAS)
P51686 (/TAS)
P51686 (/TAS)
(2 more) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
9 | P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
6 | P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) Q9NPB9 (/TAS) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
6 | P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) Q9NPB9 (/TAS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
5 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) Q9WUT7 (/IDA) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
5 | P32248 (/NAS) P32248 (/NAS) P32248 (/NAS) P32248 (/NAS) P47774 (/NAS) |
|
Cellular defense response GO:0006968
A defense response that is mediated by cells.
|
5 | P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) |
|
Lymphocyte migration into lymph node GO:0097022
The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
|
5 | P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P32248 (/TAS) P47774 (/TAS) |
|
Establishment of T cell polarity GO:0001768
The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Dendritic cell chemotaxis GO:0002407
The movement of a dendritic cell in response to an external stimulus.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Myeloid dendritic cell chemotaxis GO:0002408
The movement of a myeloid dendritic cell in response to an external stimulus.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Myeloid dendritic cell chemotaxis GO:0002408
The movement of a myeloid dendritic cell in response to an external stimulus.
|
4 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) |
|
Positive regulation of dendritic cell antigen processing and presentation GO:0002606
Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of hypersensitivity GO:0002885
Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of humoral immune response GO:0002922
Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of pseudopodium assembly GO:0031274
Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Ruffle organization GO:0031529
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Regulation of interferon-gamma production GO:0032649
Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of phosphatidylinositol 3-kinase activity GO:0043552
Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of protein kinase activity GO:0045860
Any process that activates or increases the frequency, rate or extent of protein kinase activity.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Regulation of interleukin-1 beta secretion GO:0050706
Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Release of sequestered calcium ion into cytosol GO:0051209
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of flagellated sperm motility involved in capacitation GO:0060474
The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
|
4 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
4 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) |
|
Response to nitric oxide GO:0071731
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Interleukin-12 secretion GO:0072610
The regulated release of interleukin-12 from a cell.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
4 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) |
|
Activation of GTPase activity GO:0090630
Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Mature conventional dendritic cell differentiation GO:0097029
The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Positive regulation of dendritic cell chemotaxis GO:2000510
Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of immunological synapse formation GO:2000522
Any process that activates or increases the frequency, rate or extent of immunological synapse formation.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of T cell costimulation GO:2000525
Any process that activates or increases the frequency, rate or extent of T cell costimulation.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526
Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Regulation of dendritic cell dendrite assembly GO:2000547
Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.
|
4 | P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) P32248 (/ISS) |
|
Negative regulation of dendritic cell apoptotic process GO:2000669
Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.
|
4 | P32248 (/IC) P32248 (/IC) P32248 (/IC) P32248 (/IC) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
3 | P47774 (/IMP) P51684 (/IMP) P51684 (/IMP) |
|
Dendritic cell chemotaxis GO:0002407
The movement of a dendritic cell in response to an external stimulus.
|
2 | P51684 (/TAS) P51684 (/TAS) |
|
Leukocyte migration involved in inflammatory response GO:0002523
The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
Leukocyte migration involved in inflammatory response GO:0002523
The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
2 | P51684 (/TAS) P51684 (/TAS) |
|
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
2 | P51684 (/TAS) P51684 (/TAS) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
2 | A5PLI3 (/IGI) F1QLM4 (/IGI) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
2 | A5PLI3 (/IMP) F1QLM4 (/IMP) |
|
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
|
2 | O00574 (/TAS) O00574 (/TAS) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | P51684 (/IMP) P51684 (/IMP) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | O54689 (/ISS) O54689 (/ISS) |
|
Isotype switching to IgA isotypes GO:0048290
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
Isotype switching to IgA isotypes GO:0048290
The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
2 | A0A060YGE9 (/IDA) L7UKG5 (/IDA) |
|
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | P51684 (/IDA) P51684 (/IDA) |
|
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | O54689 (/ISS) O54689 (/ISS) |
|
Positive regulation of flagellated sperm motility involved in capacitation GO:0060474
The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Lymphocyte migration GO:0072676
The movement of a lymphocyte within or between different tissues and organs of the body.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
Lymphocyte migration GO:0072676
The movement of a lymphocyte within or between different tissues and organs of the body.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
T cell migration GO:0072678
The movement of a T cell within or between different tissues and organs of the body.
|
2 | O54689 (/IDA) O54689 (/IDA) |
|
T cell migration GO:0072678
The movement of a T cell within or between different tissues and organs of the body.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Thymocyte migration GO:0072679
The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.
|
2 | O54689 (/IDA) O54689 (/IDA) |
|
Thymocyte migration GO:0072679
The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
2 | A5PLI3 (/IGI) F1QLM4 (/IGI) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
2 | A5PLI3 (/IMP) F1QLM4 (/IMP) |
|
Lymphoid lineage cell migration into thymus GO:0097535
The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.
|
2 | B0V1K7 (/IMP) Q568F5 (/IMP) |
|
DN2 thymocyte differentiation GO:1904155
The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
DN2 thymocyte differentiation GO:1904155
The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
DN3 thymocyte differentiation GO:1904156
The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
DN3 thymocyte differentiation GO:1904156
The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Regulation of T cell migration GO:2000404
Any process that modulates the frequency, rate or extent of T cell migration.
|
2 | O54689 (/IMP) O54689 (/IMP) |
|
Regulation of T cell migration GO:2000404
Any process that modulates the frequency, rate or extent of T cell migration.
|
2 | P51684 (/ISS) P51684 (/ISS) |
|
Positive regulation of dendritic cell chemotaxis GO:2000510
Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.
|
2 | P47774 (/IMP) Q5BK58 (/IMP) |
|
Positive regulation of dendritic cell chemotaxis GO:2000510
Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Establishment of T cell polarity GO:0001768
The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
|
1 | P47774 (/TAS) |
|
CD8-positive, gamma-delta intraepithelial T cell differentiation GO:0002305
The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
|
1 | Q9WUT7 (/IMP) |
|
Myeloid dendritic cell chemotaxis GO:0002408
The movement of a myeloid dendritic cell in response to an external stimulus.
|
1 | P47774 (/ISO) |
|
Lymphocyte chemotaxis across high endothelial venule GO:0002518
The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.
|
1 | P47774 (/TAS) |
|
Positive regulation of dendritic cell antigen processing and presentation GO:0002606
Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
|
1 | P47774 (/IDA) |
|
Regulation of tolerance induction to self antigen GO:0002649
Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.
|
1 | P47774 (/TAS) |
|
Positive regulation of hypersensitivity GO:0002885
Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
|
1 | P47774 (/IMP) |
|
Positive regulation of humoral immune response GO:0002922
Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
|
1 | P47774 (/IMP) |
|
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | P47774 (/TAS) |
|
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
1 | P47774 (/IMP) |
|
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
1 | Q5BK58 (/IMP) |
|
Activation of JUN kinase activity GO:0007257
The initiation of the activity of the inactive enzyme JUN kinase (JNK).
|
1 | P47774 (/IC) |
|
Positive regulation of epithelial cell migration GO:0010634
Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
|
1 | Q5BK58 (/IDA) |
|
Positive regulation of macrophage chemotaxis GO:0010759
Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
|
1 | P47774 (/NAS) |
|
Positive regulation of T cell chemotaxis GO:0010820
Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
|
1 | P47774 (/TAS) |
|
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | P47774 (/TAS) |
|
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | P47774 (/IDA) |
|
Regulation of interferon-gamma production GO:0032649
Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
|
1 | P47774 (/IMP) |
|
Positive regulation of interleukin-12 production GO:0032735
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
|
1 | P47774 (/IMP) |
|
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
|
1 | P47774 (/IC) |
|
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
1 | P47774 (/TAS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
1 | P47774 (/IC) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | P47774 (/IC) |
|
Negative thymic T cell selection GO:0045060
The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
|
1 | P47774 (/IMP) |
|
Positive regulation of T-helper 1 cell differentiation GO:0045627
Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
|
1 | P47774 (/IC) |
|
Positive regulation of receptor-mediated endocytosis GO:0048260
Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
|
1 | P47774 (/IC) |
|
Lymph node development GO:0048535
The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
|
1 | P47774 (/TAS) |
|
Homeostasis of number of cells GO:0048872
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
|
1 | P47774 (/IMP) |
|
Regulation of interleukin-1 beta secretion GO:0050706
Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
|
1 | P47774 (/IMP) |
|
Positive regulation of interleukin-1 beta secretion GO:0050718
Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
|
1 | P47774 (/IC) |
|
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
|
1 | P47774 (/NAS) |
|
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | P47774 (/IMP) |
|
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | P47774 (/TAS) |
|
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P47774 (/ISO) |
|
Response to nitric oxide GO:0071731
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
|
1 | P47774 (/TAS) |
|
Interleukin-12 secretion GO:0072610
The regulated release of interleukin-12 from a cell.
|
1 | P47774 (/IMP) |
|
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | P47774 (/IMP) |
|
Positive regulation of neutrophil chemotaxis GO:0090023
Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | P47774 (/ISO) |
|
Mature conventional dendritic cell differentiation GO:0097029
The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
|
1 | P47774 (/IMP) |
|
Negative regulation of leukocyte apoptotic process GO:2000107
Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.
|
1 | P47774 (/TAS) |
|
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
1 | P47774 (/TAS) |
|
Positive regulation of thymocyte migration GO:2000412
Any process that activates or increases the frequency, rate or extent of thymocyte migration.
|
1 | P47774 (/TAS) |
|
Positive regulation of immunological synapse formation GO:2000522
Any process that activates or increases the frequency, rate or extent of immunological synapse formation.
|
1 | P47774 (/IMP) |
|
Positive regulation of T cell costimulation GO:2000525
Any process that activates or increases the frequency, rate or extent of T cell costimulation.
|
1 | P47774 (/IMP) |
|
Positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526
Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.
|
1 | P47774 (/IMP) |
|
Regulation of dendritic cell dendrite assembly GO:2000547
Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.
|
1 | P47774 (/IC) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
12 |
A0N0Q0 (/IDA)
A0N0Q0 (/IDA)
A0N0Q0 (/IDA)
A0N0Q0 (/IDA)
J3KSS9 (/IDA)
J3KSS9 (/IDA)
J3KSS9 (/IDA)
J3KSS9 (/IDA)
P32248 (/IDA)
P32248 (/IDA)
(2 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
12 |
O00574 (/TAS)
O00574 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P32248 (/TAS)
P51684 (/TAS)
P51684 (/TAS)
P51686 (/TAS)
P51686 (/TAS)
(2 more) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
12 |
O54689 (/IDA)
O54689 (/IDA)
P32248 (/IDA)
P32248 (/IDA)
P32248 (/IDA)
P32248 (/IDA)
P47774 (/IDA)
P51684 (/IDA)
P51684 (/IDA)
P51686 (/IDA)
(2 more) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
8 | O00574 (/TAS) O00574 (/TAS) P51684 (/TAS) P51684 (/TAS) P51686 (/TAS) P51686 (/TAS) P51686 (/TAS) Q9NPB9 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P32248 (/IDA) P47774 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | O54689 (/ISO) O54689 (/ISO) P47774 (/ISO) Q9WUT7 (/ISO) |
|
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
|
4 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) |
|
Sperm principal piece GO:0097228
The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
|
4 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) |
|
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
|
4 | O54689 (/IDA) O54689 (/IDA) P51684 (/IDA) P51684 (/IDA) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
3 | O54689 (/IDA) O54689 (/IDA) P47774 (/IDA) |
|
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
2 | A0A060YGE9 (/IDA) L7UKG5 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | A0A060YGE9 (/IDA) L7UKG5 (/IDA) |
|
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
|
2 | P51684 (/IDA) P51684 (/IDA) |
|
Sperm midpiece GO:0097225
The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Sperm principal piece GO:0097228
The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Sperm plasma membrane GO:0097524
A plasma membrane that is part of a sperm cell.
|
2 | O54689 (/ISO) O54689 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P47774 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P47774 (/ISO) |