The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"DNA helicase RuvA subunit, C-terminal domain
".
FunFam 232: Ubiquitin carboxyl-terminal hydrolase A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q9VZU7 (/ISS) |
|
Lys48-specific deubiquitinase activity GO:1990380
Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
|
1 | Q9VZU7 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
|
1 | Q9VZU7 (/IMP) |
|
Ubiquitin recycling GO:0010992
Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.
|
1 | Q9VZU7 (/IMP) |
|
Free ubiquitin chain depolymerization GO:0010995
The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.
|
1 | Q9VZU7 (/IMP) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q9VZU7 (/ISS) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9VZU7 (/IMP) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q9VZU7 (/IMP) |
|
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | Q9VZU7 (/IMP) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q9VZU7 (/IDA) |
|
Protein K48-linked deubiquitination GO:0071108
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
|
1 | Q9VZU7 (/IMP) |
|
Regulation of proteasome assembly GO:0090364
Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
|
1 | Q9VZU7 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9VZU7 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9VZU7 (/HDA) |