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CATH Superfamily 1.10.8.10

Ubiquitin-associated (UBA) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA helicase RuvA subunit, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 179: Defective in cullin neddylation protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q12395 (/IPI) Q12395 (/IPI)
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
 2 Q12395 (/IMP) Q12395 (/IMP)
Ubiquitin conjugating enzyme binding GO:0031624
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
 2 Q12395 (/IDA) Q12395 (/IDA)
Ubiquitin-like protein binding GO:0032182
Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
 2 Q12395 (/IDA) Q12395 (/IDA)
Cullin family protein binding GO:0097602
Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).
 2 Q12395 (/IMP) Q12395 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
 2 Q12395 (/IDA) Q12395 (/IDA)
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
 2 Q12395 (/IGI) Q12395 (/IGI)
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
 2 Q12395 (/IMP) Q12395 (/IMP)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
 2 Q12395 (/IMP) Q12395 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.