The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA helicase RuvA subunit, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Elongation factor Ts

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
171 P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA)
(161 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
171 P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI) P0A6P1 (/IPI)
(161 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
171 P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA)
(161 more)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
8 Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS)
Mannan binding GO:2001065
Interacting selectively and non-covalently with mannan.
5 Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
2 Q9SZD6 (/IDA) Q9SZD6 (/IDA)
Translation elongation factor activity GO:0003746
Functions in chain elongation during polypeptide synthesis at the ribosome.
1 Q9HGL5 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
8 Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS) Q9KPV3 (/ISS)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9SZD6 (/IEP) Q9SZD6 (/IEP)
Oxidative phosphorylation GO:0006119
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
1 Q57W99 (/IMP)
Mitochondrial translational elongation GO:0070125
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
1 Q9HGL5 (/IGI)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
172 O51148 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA) P0A6P1 (/IDA)
(162 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
171 P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA)
(161 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
171 P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA) P0A6P1 (/HDA)
(161 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
9 P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA) P9WNM1 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
5 Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA) Q9CDR5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q57W99 (/IDA) Q5XF75 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q9SZD6 (/IDA) Q9SZD6 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q9SZD6 (/IDA) Q9SZD6 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
2 Q9SZD6 (/IDA) Q9SZD6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q57W99 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4FXY8 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9HGL5 (/IGI)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q57W99 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q4FXY8 (/ISO)