The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SAP domain
".
FunFam 15: 3'-5' exoribonuclease 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q7TMF2 (/IPI) Q8IV48 (/IPI) Q8IV48 (/IPI) |
|
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Histone pre-mRNA stem-loop binding GO:0071207
Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
3'-5'-exoribonuclease activity GO:0000175
Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
|
2 | Q8IV48 (/TAS) Q8IV48 (/TAS) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
2 | Q8IV48 (/IDA) Q8IV48 (/IDA) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
2 | Q5FVR4 (/ISS) Q7TMF2 (/ISS) |
|
3'-5' exonuclease activity GO:0008408
Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
|
1 | Q7TMF2 (/ISO) |
|
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
|
1 | Q7TMF2 (/IDA) |
|
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
|
1 | Q7TMF2 (/IDA) |
|
Histone pre-mRNA stem-loop binding GO:0071207
Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs.
|
1 | Q7TMF2 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RRNA 3'-end processing GO:0031125
Any process involved in forming the mature 3' end of an rRNA molecule.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
2 | Q8IV48 (/TAS) Q8IV48 (/TAS) |
|
RRNA 3'-end processing GO:0031125
Any process involved in forming the mature 3' end of an rRNA molecule.
|
1 | Q7TMF2 (/IDA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
4 | Q5FVR4 (/ISS) Q7TMF2 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q5FVR4 (/ISS) Q7TMF2 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
3 | Q7TMF2 (/IDA) Q8IV48 (/IDA) Q8IV48 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q7TMF2 (/IDA) Q8IV48 (/IDA) Q8IV48 (/IDA) |
|
Histone pre-mRNA 3'end processing complex GO:0071204
A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.
|
3 | Q5FVR4 (/ISS) Q8IV48 (/ISS) Q8IV48 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q8IV48 (/TAS) Q8IV48 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q7TMF2 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q7TMF2 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q7TMF2 (/ISO) |
|
Histone pre-mRNA 3'end processing complex GO:0071204
A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.
|
1 | Q7TMF2 (/IDA) |