The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"SAP domain
".
FunFam 13: SAP domain-containing ribonucleoprotein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
13 |
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
P82979 (/IPI)
(3 more) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
11 |
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
P82979 (/HDA)
(1 more) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | Q9D1J3 (/IDA) Q9D1J3 (/IDA) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q9D1J3 (/IDA) Q9D1J3 (/IDA) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q9D1J3 (/IMP) Q9D1J3 (/IMP) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
2 | Q9D1J3 (/IPI) Q9D1J3 (/IPI) |
|
RS domain binding GO:0050733
Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.
|
2 | Q9D1J3 (/IPI) Q9D1J3 (/IPI) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
14 |
Q498U4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
(4 more) |
|
RNA export from nucleus GO:0006405
The directed movement of RNA from the nucleus to the cytoplasm.
|
11 |
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
(1 more) |
|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
11 |
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
(1 more) |
|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
11 |
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
(1 more) |
|
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
|
11 |
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
(1 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q9D1J3 (/IDA) Q9D1J3 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q9D1J3 (/IMP) Q9D1J3 (/IMP) |
|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
2 | Q9D1J3 (/ISO) Q9D1J3 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription export complex GO:0000346
The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.
|
14 |
Q498U4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
(4 more) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
14 |
Q498U4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
Q5R4V4 (/ISS)
(4 more) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
12 |
F8VZQ9 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
(2 more) |
|
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
|
12 |
F8VZQ9 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
(2 more) |
|
Transcription export complex GO:0000346
The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.
|
11 |
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
P82979 (/IDA)
(1 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
P82979 (/NAS)
(1 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
11 |
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
P82979 (/TAS)
(1 more) |
|
Transcription export complex GO:0000346
The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.
|
2 | Q9D1J3 (/ISO) Q9D1J3 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q9D1J3 (/IDA) Q9D1J3 (/IDA) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
2 | Q9D1J3 (/ISO) Q9D1J3 (/ISO) |
|
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
|
2 | Q9D1J3 (/ISO) Q9D1J3 (/ISO) |