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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: Cytochrome P450 71D8

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ent-cassadiene hydroxylase. [EC: 1.14.14.69]
Ent-cassa-12,15-diene + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) = ent-3-beta-hydroxycassa-12,15-dien-2-one + 3 [oxidized NADPH- -hemoprotein reductase] + 4 H(2)O.
  • A cytochrome P450 (heme-thiolate) protein isolated from the plant Oryza sativa (rice) that is involved in phytocassanes biosynthesis.
  • Depending on the order of activities, the enzyme may form either ent- cassa-12,15-dien-2-one or ent-cassa-12,15-diene-2-beta,3-beta-diol as an intermediate.
 4 A0A0E0NGP1 A0A0E0NGP1 Q6YV88 Q6YV88
Ent-isokaurene C2/C3-hydroxylase. [EC: 1.14.14.76]
Ent-isokaurene + 2 O(2) + 2 [reduced NADPH--hemoprotein reductase] = ent- isokaurene-2-beta,3-beta-diol + [oxidized NADPH--hemoprotein reductase] + 2 H(2)O.
  • This cytochrome P450 (heme thiolate) enzyme has been characterized from the plant Oryza sativa (rice).
  • It may be involved in production of oryzadione.
  • Formerly EC 1.14.13.143.
 1 A3A871