View in Gene3D

CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 59: Cytochrome P450 monooxygenase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Monacolin L hydroxylase. [EC: 1.14.14.125]
Monacolin L acid + O(2) + [reduced NADPH--hemoprotein reductase] = monacolin J acid + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein.
  • The enzyme from fungi also catalyzes the reaction of EC 1.14.14.124.
  • Formerly EC 1.14.13.198.
 2 Q3S2T8 Q9Y7C8
Dihydromonacolin L hydroxylase. [EC: 1.14.14.124]
Dihydromonacolin L acid + O(2) + [reduced NADPH--hemoprotein reductase] = monacolin L acid + [oxidized NADPH--hemoprotein reductase] + 2 H(2)O.
  • A cytochrome P450 (heme-thiolate) protein.
  • The dehydration of 3-alpha-hydroxy-3,5-dihydromonacolin L acid is believed to be spontaneous.
  • The enzyme from fungi also catalyzes the reaction of EC 1.14.14.125.
  • Formerly EC 1.14.13.197.
 2 Q3S2T8 Q9Y7C8