The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P1 Nuclease
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phospholipase C. [EC: 3.1.4.3]
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
  • The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol.
  • The enzyme from seminal plasma does not act on phosphatidylinositol.
29 A0A0A1SLS6 A0A0F5RTP8 A0A150DUU4 A0A1J9XMT7 A0A1J9Y7V4 A0A229MJ30 A0A243I0U7 A0A243NC68 A0A2Z2CQ20 A0A3G5UKE7
(19 more...)
Aspergillus nuclease S(1). [EC: 3.1.30.1]
Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products.
  • Preference for single-stranded substrate.
  • Similar enzymes: Neurospora crassa nuclease, mung bean nuclease, Penicillium citrinum nuclease P1.
  • Formerly EC 3.1.4.21.
8 A0A178WKD4 F4JJL0 F4JJL3 P24021 P24289 Q8LDW6 Q9C9G4 Q9SXA6
3'-nucleotidase. [EC: 3.1.3.6]
A 3'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
  • Wide specificity for 3'-nucleotides.
1 P24504