The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rho GTPase activation protein
".
FunFam 13: SLIT-ROBO Rho GTPase activating protein 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
O43295 (/IPI)
O43295 (/IPI)
O43295 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
Q7Z6B7 (/IPI)
(2 more) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
10 | O43295 (/TAS) O43295 (/TAS) O43295 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q91Z69 (/IDA) |
|
Rho GTPase binding GO:0017048
Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
|
1 | Q91Z69 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of small GTPase mediated signal transduction GO:0051056
Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
|
10 | O43295 (/TAS) O43295 (/TAS) O43295 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) |
|
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
|
1 | Q91Z69 (/IDA) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q91Z69 (/IDA) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | O43295 (/TAS) O43295 (/TAS) O43295 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) Q7Z6B7 (/TAS) |