The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rho GTPase activation protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 122: Rho GTPase Activating protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
3 H2KZS7 (/IDA) O01585 (/IDA) Q965S4 (/IDA)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
3 H2KZS7 (/IGI) O01585 (/IGI) Q965S4 (/IGI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cortical actin cytoskeleton organization GO:0030866
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
3 H2KZS7 (/IGI) O01585 (/IGI) Q965S4 (/IGI)
Regulation of actin filament-based process GO:0032970
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
3 H2KZS7 (/IGI) O01585 (/IGI) Q965S4 (/IGI)
Regulation of actin filament-based process GO:0032970
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
3 H2KZS7 (/IMP) O01585 (/IMP) Q965S4 (/IMP)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
3 H2KZS7 (/IGI) O01585 (/IGI) Q965S4 (/IGI)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 O01585 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 O01585 (/IDA)