View in Gene3D

CATH Superfamily 1.10.533.10

Death Domain, Fas

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Death Domain, Fas
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 151: Viral CASP8 and FADD-like apoptosis regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 3 Q98325 (/IPI) Q98325 (/IPI) Q98325 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Suppression by virus of host apoptotic process GO:0019050
Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.
 3 Q98325 (/IDA) Q98325 (/IDA) Q98325 (/IDA)
Suppression by virus of host autophagy GO:0039521
Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.
 3 Q98325 (/IDA) Q98325 (/IDA) Q98325 (/IDA)
Suppression by virus of host NF-kappaB transcription factor activity GO:0039644
Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity.
 3 Q98325 (/IDA) Q98325 (/IDA) Q98325 (/IDA)
Positive regulation of necroptotic process GO:0060545
Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
 3 Q98325 (/IMP) Q98325 (/IMP) Q98325 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Host cell cytoplasm GO:0030430
The cytoplasm of a host cell.
 3 Q98325 (/IDA) Q98325 (/IDA) Q98325 (/IDA)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
 3 Q98325 (/IDA) Q98325 (/IDA) Q98325 (/IDA)