The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 939: Z-DNA binding protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Left-handed Z-DNA binding GO:0003692
Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.
9 F1QXK7 (/IDA) Q5GQ94 (/IDA) Q5NE09 (/IDA) Q5NE10 (/IDA) Q5NE11 (/IDA) Q5NE12 (/IDA) Q5NE13 (/IDA) Q5NE14 (/IDA) Q5NE15 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
9 F1QXK7 (/IDA) Q5GQ94 (/IDA) Q5NE09 (/IDA) Q5NE10 (/IDA) Q5NE11 (/IDA) Q5NE12 (/IDA) Q5NE13 (/IDA) Q5NE14 (/IDA) Q5NE15 (/IDA)
Eukaryotic translation initiation factor 2alpha kinase activity GO:0004694
Catalysis of the reaction: ATP +
1 Q0H740 (/IMP)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q0H740 (/IDA)
Peptidyl-serine autophosphorylation GO:0036289
The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.
1 Q0H740 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q0H740 (/IDA)