The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 938: eIF-2-alpha kinase GCN2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eukaryotic translation initiation factor 2alpha kinase activity GO:0004694
Catalysis of the reaction: ATP +
2 Q550L8 (/ISS) Q558U1 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q550L8 (/IC) Q558U1 (/IC)
Eukaryotic translation initiation factor 2alpha kinase activity GO:0004694
Catalysis of the reaction: ATP +
1 A0A0B4KHX7 (/IDA)
Eukaryotic translation initiation factor 2alpha kinase activity GO:0004694
Catalysis of the reaction: ATP +
1 Q558U1 (/IMP)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cell size GO:0045793
Any process that increases cell size.
5 A0A0B4KHX7 (/IGI) O01712 (/IGI) O61651 (/IGI) Q7YU14 (/IGI) Q9V9X8 (/IGI)
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
2 Q550L8 (/IGI) Q558U1 (/IGI)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
2 Q550L8 (/IGI) Q558U1 (/IGI)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q558U1 (/IMP)
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
1 Q558U1 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 A0A0B4KHX7 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q558U1 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q550L8 (/ISS)
Regulation of translational initiation by eIF2 alpha phosphorylation GO:0010998
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
1 A0A0B4KHX7 (/IC)
Regulation of translational initiation by eIF2 alpha phosphorylation GO:0010998
Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
1 A0A0B4KHX7 (/IDA)
CAMP-mediated signaling GO:0019933
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
1 Q558U1 (/IMP)
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 Q558U1 (/IMP)
Negative regulation of aggregate size involved in sorocarp development GO:0031158
Any process that decreases the size of the aggregate formed during sorocarp formation.
1 Q558U1 (/IMP)
MRNA stabilization GO:0048255
Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
1 Q558U1 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 A0A0B4KHX7 (/IC)